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Pig-to-human heart xenotransplantation in two recently deceased human recipients.
Moazami N, Stern JM, Khalil K, Kim JI, Narula N, Mangiola M, Weldon EP, Kagermazova L, James L, Lawson N, Piper GL, Sommer PM, Reyentovich A, Bamira D, Saraon T, Kadosh BS, DiVita M, Goldberg RI, Hussain ST, Chan J, Ngai J, Jan T, Ali NM, Tatapudi VS, Segev DL, Bisen S, Jaffe IS, Piegari B, Kowalski H, Kokkinaki M, Monahan J, Sorrells L, Burdorf L, Boeke JD, Pass H, Goparaju C, Keating B, Ayares D, Lorber M, Griesemer A, Mehta SA, Smith DE, Montgomery RA. Moazami N, et al. Among authors: burdorf l. Nat Med. 2023 Aug;29(8):1989-1997. doi: 10.1038/s41591-023-02471-9. Epub 2023 Jul 24. Nat Med. 2023. PMID: 37488288
Pig-to-baboon liver xenoperfusion utilizing GalTKO.hCD46 pigs and glycoprotein Ib blockade.
LaMattina JC, Burdorf L, Zhang T, Rybak E, Cheng X, Munivenkatappa R, Salles II, Broos K, Sievert E, McCormick B, Decarlo M, Ayares D, Deckmyn H, Azimzadeh AM, Pierson RN 3rd, Barth RN. LaMattina JC, et al. Among authors: burdorf l. Xenotransplantation. 2014 May-Jun;21(3):274-86. doi: 10.1111/xen.12093. Epub 2014 Mar 17. Xenotransplantation. 2014. PMID: 24628649 Free PMC article.
Meta-analysis of the independent and cumulative effects of multiple genetic modifications on pig lung xenograft performance during ex vivo perfusion with human blood.
Harris DG, Quinn KJ, French BM, Schwartz E, Kang E, Dahi S, Phelps CJ, Ayares DL, Burdorf L, Azimzadeh AM, Pierson RN 3rd. Harris DG, et al. Among authors: burdorf l. Xenotransplantation. 2015 Mar-Apr;22(2):102-11. doi: 10.1111/xen.12149. Epub 2014 Dec 2. Xenotransplantation. 2015. PMID: 25470239 Free PMC article.
Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein.
Azimzadeh AM, Kelishadi SS, Ezzelarab MB, Singh AK, Stoddard T, Iwase H, Zhang T, Burdorf L, Sievert E, Avon C, Cheng X, Ayares D, Horvath KA, Corcoran PC, Mohiuddin MM, Barth RN, Cooper DK, Pierson RN 3rd. Azimzadeh AM, et al. Among authors: burdorf l. Xenotransplantation. 2015 Jul-Aug;22(4):310-6. doi: 10.1111/xen.12176. Epub 2015 Jul 14. Xenotransplantation. 2015. PMID: 26174749 Free PMC article.
N-glycolylneuraminic acid knockout reduces erythrocyte sequestration and thromboxane elaboration in an ex vivo pig-to-human xenoperfusion model.
Cimeno A, Hassanein W, French BM, Powell JM, Burdorf L, Goloubeva O, Cheng X, Parsell DM, Ramsoondar J, Kuravi K, Vaught T, Uluer MC, Redding E, O'Neill N, Laird C, Hershfeld A, Tatarov I, Thomas K, Ayares D, Azimzadeh AM, Pierson RN 3rd, Barth RN, LaMattina JC. Cimeno A, et al. Among authors: burdorf l. Xenotransplantation. 2017 Nov;24(6):10.1111/xen.12339. doi: 10.1111/xen.12339. Epub 2017 Sep 22. Xenotransplantation. 2017. PMID: 28940313 Free PMC article.
P- and E-selectin receptor antagonism prevents human leukocyte adhesion to activated porcine endothelial monolayers and attenuates porcine endothelial damage.
Laird CT, Hassanein W, O'Neill NA, French BM, Cheng X, Fogler WE, Magnani JL, Parsell D, Cimeno A, Phelps CJ, Ayares D, Burdorf L, Azimzadeh AM, Pierson RN 3rd. Laird CT, et al. Among authors: burdorf l. Xenotransplantation. 2018 Mar;25(2):e12381. doi: 10.1111/xen.12381. Epub 2018 Jan 23. Xenotransplantation. 2018. PMID: 29359469 Free PMC article.
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models.
Connolly MR, Kuravi K, Burdorf L, Sorrells L, Morrill B, Cimeno A, Vaught T, Dandro A, Sendil S, Habibabady ZA, Monahan J, Li T, LaMattina J, Eyestone W, Ayares D, Phelps C, Azimzadeh AM, Pierson RN 3rd. Connolly MR, et al. Among authors: burdorf l. Xenotransplantation. 2021 Nov;28(6):e12712. doi: 10.1111/xen.12712. Epub 2021 Oct 17. Xenotransplantation. 2021. PMID: 34657336 Free PMC article.
hEPCR.hTBM.hCD47.hHO-1 with donor clodronate and DDAVP treatment improves perfusion and function of GalTKO.hCD46 porcine livers perfused with human blood.
Cimeno A, Kuravi K, Sorrells L, Dandro A, Sendil S, Burdorf L, Parsell DM, Eyestone W, Phelps C, Ayares D, Azimzadeh AM, Pierson RN 3rd, Barth RN, LaMattina JC. Cimeno A, et al. Among authors: burdorf l. Xenotransplantation. 2022 Mar;29(2):e12731. doi: 10.1111/xen.12731. Epub 2022 Feb 15. Xenotransplantation. 2022. PMID: 35166407 Free PMC article.
62 results