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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases.
Xie MM, Dai B, Hackney JA, Sun T, Zhang J, Jackman JK, Jeet S, Irizarry-Caro RA, Fu Y, Liang Y, Bender H, Shamir ER, Keir ME, Bevers J, Nakamura G, Townsend MJ, Fox DA, Scherl A, Lee WP, Martin F, Godowski PJ, Pappu R, Yi T. Xie MM, et al. Among authors: pappu r. Cell Rep Med. 2023 Aug 15;4(8):101130. doi: 10.1016/j.xcrm.2023.101130. Epub 2023 Jul 24. Cell Rep Med. 2023. PMID: 37490914 Free PMC article.
Biomolecular condensates form spatially inhomogeneous network fluids.
Dar F, Cohen SR, Mitrea DM, Phillips AH, Nagy G, Leite WC, Stanley CB, Choi JM, Kriwacki RW, Pappu RV. Dar F, et al. Among authors: pappu rv. Nat Commun. 2024 Apr 22;15(1):3413. doi: 10.1038/s41467-024-47602-z. Nat Commun. 2024. PMID: 38649740 Free PMC article.
Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient.
King MR, Ruff KM, Lin AZ, Pant A, Farag M, Lalmansingh JM, Wu T, Fossat MJ, Ouyang W, Lew MD, Lundberg E, Vahey MD, Pappu RV. King MR, et al. Among authors: pappu rv. Cell. 2024 Apr 11;187(8):1889-1906.e24. doi: 10.1016/j.cell.2024.02.029. Epub 2024 Mar 18. Cell. 2024. PMID: 38503281 Free article.
Metastable condensates suppress conversion to amyloid fibrils.
Das T, Zaidi F, Farag M, Ruff KM, Messing J, Taylor JP, Pappu RV, Mittag T. Das T, et al. Among authors: pappu rv. bioRxiv [Preprint]. 2024 Mar 3:2024.02.28.582569. doi: 10.1101/2024.02.28.582569. bioRxiv. 2024. PMID: 38464104 Free PMC article. Preprint.
Emergent microenvironments of nucleoli.
King MR, Ruff KM, Pappu RV. King MR, et al. Among authors: pappu rv. Nucleus. 2024 Dec;15(1):2319957. doi: 10.1080/19491034.2024.2319957. Epub 2024 Mar 5. Nucleus. 2024. PMID: 38443761 Free PMC article. Review.
233 results