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Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.
Chatzinakos C, Pernia CD, Morrison FG, Iatrou A, McCullough KM, Schuler H, Snijders C, Bajaj T, DiPietro CP, Soliva Estruch M, Gassen NC, Anastasopoulos C, Bharadwaj RA, Bowlby BC, Hartmann J, Maihofer AX, Nievergelt CM, Ressler NM, Wolf EJ; Traumatic Stress Brain Research Group; PTSD BrainOmics Project of the PsychENCODE Consortium; PTSD Working Group of the Psychiatric Genomics Consortium; Carlezon WA Jr, Krystal JH, Kleinman JE, Girgenti MJ, Huber BR, Kellis M, Logue MW, Miller MW, Ressler KJ, Daskalakis NP. Chatzinakos C, et al. Among authors: huber br. Am J Psychiatry. 2023 Oct 1;180(10):739-754. doi: 10.1176/appi.ajp.20220478. Epub 2023 Jul 26. Am J Psychiatry. 2023. PMID: 37491937
Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence.
Holmes SE, Girgenti MJ, Davis MT, Pietrzak RH, DellaGioia N, Nabulsi N, Matuskey D, Southwick S, Duman RS, Carson RE, Krystal JH, Esterlis I; Traumatic Stress Brain Study Group. Holmes SE, et al. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8390-8395. doi: 10.1073/pnas.1701749114. Epub 2017 Jul 17. Proc Natl Acad Sci U S A. 2017. PMID: 28716937 Free PMC article.
VA's National PTSD Brain Bank: a National Resource for Research.
Friedman MJ, Huber BR, Brady CB, Ursano RJ, Benedek DM, Kowall NW, McKee AC; Traumatic Stress Brain Research Group. Friedman MJ, et al. Among authors: huber br. Curr Psychiatry Rep. 2017 Aug 25;19(10):73. doi: 10.1007/s11920-017-0822-6. Curr Psychiatry Rep. 2017. PMID: 28840457 Review.
Reduced interleukin 1A gene expression in the dorsolateral prefrontal cortex of individuals with PTSD and depression.
Morrison FG, Miller MW, Wolf EJ, Logue MW, Maniates H, Kwasnik D, Cherry JD, Svirsky S, Restaino A, Hildebrandt A, Aytan N, Stein TD, Alvarez VE, McKee AC; Traumatic Stress Brain Study Group; Huber BR. Morrison FG, et al. Among authors: huber br. Neurosci Lett. 2019 Jan 23;692:204-209. doi: 10.1016/j.neulet.2018.10.027. Epub 2018 Oct 23. Neurosci Lett. 2019. PMID: 30366016 Free PMC article.
An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.
Logue MW, Miller MW, Wolf EJ, Huber BR, Morrison FG, Zhou Z, Zheng Y, Smith AK, Daskalakis NP, Ratanatharathorn A, Uddin M, Nievergelt CM, Ashley-Koch AE, Baker DG, Beckham JC, Garrett ME, Boks MP, Geuze E, Grant GA, Hauser MA, Kessler RC, Kimbrel NA, Maihofer AX, Marx CE, Qin XJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Ware EB, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Hayes JP, Verfaellie M; Traumatic Stress Brain Study Group. Logue MW, et al. Among authors: huber br. Clin Epigenetics. 2020 Mar 14;12(1):46. doi: 10.1186/s13148-020-0820-0. Clin Epigenetics. 2020. PMID: 32171335 Free PMC article.
Klotho, PTSD, and advanced epigenetic age in cortical tissue.
Wolf EJ, Chen CD, Zhao X, Zhou Z, Morrison FG, Daskalakis NP, Stone A, Schichman S, Grenier JG, Fein-Schaffer D, Huber BR; Traumatic Stress Brain Research Group; Abraham CR, Miller MW, Logue MW. Wolf EJ, et al. Among authors: huber br. Neuropsychopharmacology. 2021 Mar;46(4):721-730. doi: 10.1038/s41386-020-00884-5. Epub 2020 Oct 23. Neuropsychopharmacology. 2021. PMID: 33096543 Free PMC article.
Transcriptomic organization of the human brain in post-traumatic stress disorder.
Girgenti MJ, Wang J, Ji D, Cruz DA; Traumatic Stress Brain Research Group; Stein MB, Gelernter J, Young KA, Huber BR, Williamson DE, Friedman MJ, Krystal JH, Zhao H, Duman RS. Girgenti MJ, et al. Among authors: huber br. Nat Neurosci. 2021 Jan;24(1):24-33. doi: 10.1038/s41593-020-00748-7. Epub 2020 Dec 21. Nat Neurosci. 2021. PMID: 33349712
Gene expression in the dorsolateral and ventromedial prefrontal cortices implicates immune-related gene networks in PTSD.
Logue MW, Zhou Z, Morrison FG, Wolf EJ, Daskalakis NP, Chatzinakos C, Georgiadis F, Labadorf AT, Girgenti MJ, Young KA, Williamson DE, Zhao X, Grenier JG; Traumatic Stress Brain Research Group; Huber BR, Miller MW. Logue MW, et al. Among authors: huber br. Neurobiol Stress. 2021 Sep 20;15:100398. doi: 10.1016/j.ynstr.2021.100398. eCollection 2021 Nov. Neurobiol Stress. 2021. PMID: 34646915 Free PMC article.
96 results