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Page 1
The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis.
Shmuel-Galia L, Humphries F, Vierbuchen T, Jiang Z, Santos N, Johnson J, Shklyar B, Joannas L, Mustone N, Sherman S, Ward D, Houghton J, Baer CE, O'Hara A, Henao-Mejia J, Hoebe K, Fitzgerald KA. Shmuel-Galia L, et al. Among authors: joannas l. Cell Metab. 2023 Aug 8;35(8):1441-1456.e9. doi: 10.1016/j.cmet.2023.06.019. Epub 2023 Jul 25. Cell Metab. 2023. PMID: 37494932
Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation.
Chandra A, Yoon S, Michieletto MF, Goldman N, Ferrari EK, Abedi M, Johnson I, Fasolino M, Pham K, Joannas L, Kee BL, Henao-Mejia J, Vahedi G. Chandra A, et al. Among authors: joannas l. Immunity. 2023 Jul 11;56(7):1451-1467.e12. doi: 10.1016/j.immuni.2023.05.004. Epub 2023 May 31. Immunity. 2023. PMID: 37263273 Free PMC article.
The miR-181 family regulates colonic inflammation through its activity in the intestinal epithelium.
Jimenez MT, Clark ML, Wright JM, Michieletto MF, Liu S, Erickson I, Dohnalova L, Uhr GT, Tello-Cajiao J, Joannas L, Williams A, Gagliani N, Bewtra M, Tomov VT, Thaiss CA, Henao-Mejia J. Jimenez MT, et al. Among authors: joannas l. J Exp Med. 2022 Dec 5;219(12):e20212278. doi: 10.1084/jem.20212278. Epub 2022 Sep 8. J Exp Med. 2022. PMID: 36074090 Free PMC article.
Multiscale 3D genome organization underlies ILC2 ontogenesis and allergic airway inflammation.
Michieletto MF, Tello-Cajiao JJ, Mowel WK, Chandra A, Yoon S, Joannas L, Clark ML, Jimenez MT, Wright JM, Lundgren P, Williams A, Thaiss CA, Vahedi G, Henao-Mejia J. Michieletto MF, et al. Among authors: joannas l. Nat Immunol. 2023 Jan;24(1):42-54. doi: 10.1038/s41590-022-01295-y. Epub 2022 Sep 1. Nat Immunol. 2023. PMID: 36050414 Free PMC article.
Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
Bjanes E, Sillas RG, Matsuda R, Demarco B, Fettrelet T, DeLaney AA, Kornfeld OS, Lee BL, Rodríguez López EM, Grubaugh D, Wynosky-Dolfi MA, Philip NH, Krespan E, Tovar D, Joannas L, Beiting DP, Henao-Mejia J, Schaefer BC, Chen KW, Broz P, Brodsky IE. Bjanes E, et al. Among authors: joannas l. PLoS Pathog. 2021 Oct 14;17(10):e1009967. doi: 10.1371/journal.ppat.1009967. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34648590 Free PMC article.
RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
Chen KW, Demarco B, Ramos S, Heilig R, Goris M, Grayczyk JP, Assenmacher CA, Radaelli E, Joannas LD, Henao-Mejia J, Tacchini-Cottier F, Brodsky IE, Broz P. Chen KW, et al. Among authors: joannas ld. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2101189118. doi: 10.1073/pnas.2101189118. Proc Natl Acad Sci U S A. 2021. PMID: 34260403 Free PMC article.
Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity.
Kozik P, Gros M, Itzhak DN, Joannas L, Heurtebise-Chrétien S, Krawczyk PA, Rodríguez-Silvestre P, Alloatti A, Magalhaes JG, Del Nery E, Borner GHH, Amigorena S. Kozik P, et al. Among authors: joannas l. Cell Rep. 2020 Jul 14;32(2):107905. doi: 10.1016/j.celrep.2020.107905. Cell Rep. 2020. PMID: 32668257 Free PMC article.
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.
Gehrmann U, Burbage M, Zueva E, Goudot C, Esnault C, Ye M, Carpier JM, Burgdorf N, Hoyler T, Suarez G, Joannas L, Heurtebise-Chrétien S, Durand S, Panes R, Bellemare-Pelletier A, Sáez PJ, Aprahamian F, Lefevre D, Adoue V, Zine El Aabidine A, Muhammad Ahmad M, Hivroz C, Joffre O, Cammas F, Kroemer G, Gagnon E, Andrau JC, Amigorena S. Gehrmann U, et al. Among authors: joannas l. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25839-25849. doi: 10.1073/pnas.1901639116. Epub 2019 Nov 27. Proc Natl Acad Sci U S A. 2019. PMID: 31776254 Free PMC article.
The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs.
Virtue AT, McCright SJ, Wright JM, Jimenez MT, Mowel WK, Kotzin JJ, Joannas L, Basavappa MG, Spencer SP, Clark ML, Eisennagel SH, Williams A, Levy M, Manne S, Henrickson SE, Wherry EJ, Thaiss CA, Elinav E, Henao-Mejia J. Virtue AT, et al. Among authors: joannas l. Sci Transl Med. 2019 Jun 12;11(496):eaav1892. doi: 10.1126/scitranslmed.aav1892. Sci Transl Med. 2019. PMID: 31189717 Free PMC article.
The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection.
Kotzin JJ, Iseka F, Wright J, Basavappa MG, Clark ML, Ali MA, Abdel-Hakeem MS, Robertson TF, Mowel WK, Joannas L, Neal VD, Spencer SP, Syrett CM, Anguera MC, Williams A, Wherry EJ, Henao-Mejia J. Kotzin JJ, et al. Among authors: joannas l. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11916-11925. doi: 10.1073/pnas.1819457116. Epub 2019 May 28. Proc Natl Acad Sci U S A. 2019. PMID: 31138702 Free PMC article.
19 results