Oro AE - Search Results

1

Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases.

Ober-Reynolds B, Wang C, Ko JM, Rios EJ, Aasi SZ, Davis MM, Oro AE, Greenleaf WJ. Ober-Reynolds B, et al. Among authors: oro ae. Nat Genet. 2023 Aug;55(8):1288-1300. doi: 10.1038/s41588-023-01445-4. Epub 2023 Jul 27. Nat Genet. 2023. PMID: 37500727

2

LY6D marks pre-existing resistant basosquamous tumor subpopulations.

Haensel D, Gaddam S, Li NY, Gonzalez F, Patel T, Cloutier JM, Sarin KY, Tang JY, Rieger KE, Aasi SZ, Oro AE. Haensel D, et al. Among authors: oro ae. Nat Commun. 2022 Dec 6;13(1):7520. doi: 10.1038/s41467-022-35020-y. Nat Commun. 2022. PMID: 36473848 Free PMC article.

3

Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche.

Haensel D, Daniel B, Gaddam S, Pan C, Fabo T, Bjelajac J, Jussila AR, Gonzalez F, Li NY, Chen Y, Hou J, Patel T, Aasi S, Satpathy AT, Oro AE. Haensel D, et al. Among authors: oro ae. Nat Commun. 2023 May 10;14(1):2685. doi: 10.1038/s41467-023-37993-w. Nat Commun. 2023. PMID: 37164949 Free PMC article.

4

LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription.

Mirza AN, McKellar SA, Urman NM, Brown AS, Hollmig T, Aasi SZ, Oro AE. Mirza AN, et al. Among authors: oro ae. Cell. 2019 Jan 10;176(1-2):198-212.e15. doi: 10.1016/j.cell.2018.10.054. Epub 2018 Nov 29. Cell. 2019. PMID: 30503211 Free PMC article.

5

Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas.

Whitson RJ, Lee A, Urman NM, Mirza A, Yao CY, Brown AS, Li JR, Shankar G, Fry MA, Atwood SX, Lee EY, Hollmig ST, Aasi SZ, Sarin KY, Scott MP, Epstein EH Jr, Tang JY, Oro AE. Whitson RJ, et al. Among authors: oro ae. Nat Med. 2018 Mar;24(3):271-281. doi: 10.1038/nm.4476. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400712 Free PMC article.

6

AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma.

Yao CD, Haensel D, Gaddam S, Patel T, Atwood SX, Sarin KY, Whitson RJ, McKellar S, Shankar G, Aasi S, Rieger K, Oro AE. Yao CD, et al. Among authors: oro ae. Nat Commun. 2020 Oct 8;11(1):5079. doi: 10.1038/s41467-020-18762-5. Nat Commun. 2020. PMID: 33033234 Free PMC article.

7

c-FOS drives reversible basal to squamous cell carcinoma transition.

Kuonen F, Li NY, Haensel D, Patel T, Gaddam S, Yerly L, Rieger K, Aasi S, Oro AE. Kuonen F, et al. Among authors: oro ae. Cell Rep. 2021 Oct 5;37(1):109774. doi: 10.1016/j.celrep.2021.109774. Cell Rep. 2021. PMID: 34610301 Free PMC article.

8

Phase II Open-Label, Single-Arm Trial to Investigate the Efficacy and Safety of Topical Remetinostat Gel in Patients with Basal Cell Carcinoma.

Kilgour JM, Shah A, Urman NM, Eichstadt S, Do HN, Bailey I, Mirza A, Li S, Oro AE, Aasi SZ, Sarin KY. Kilgour JM, et al. Among authors: oro ae. Clin Cancer Res. 2021 Sep 1;27(17):4717-4725. doi: 10.1158/1078-0432.CCR-21-0560. Epub 2021 Aug 6. Clin Cancer Res. 2021. PMID: 34362809 Free PMC article. Clinical Trial.

9

Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata.

Kennedy Crispin M, Ko JM, Craiglow BG, Li S, Shankar G, Urban JR, Chen JC, Cerise JE, Jabbari A, Winge MC, Marinkovich MP, Christiano AM, Oro AE, King BA. Kennedy Crispin M, et al. Among authors: oro ae. JCI Insight. 2016 Sep 22;1(15):e89776. doi: 10.1172/jci.insight.89776. JCI Insight. 2016. PMID: 27699252 Free PMC article.

10

Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment.

Mirza AN, Fry MA, Urman NM, Atwood SX, Roffey J, Ott GR, Chen B, Lee A, Brown AS, Aasi SZ, Hollmig T, Ator MA, Dorsey BD, Ruggeri BR, Zificsak CA, Sirota M, Tang JY, Butte A, Epstein E, Sarin KY, Oro AE. Mirza AN, et al. Among authors: oro ae. JCI Insight. 2017 Nov 2;2(21):e97071. doi: 10.1172/jci.insight.97071. JCI Insight. 2017. PMID: 29093271 Free PMC article.

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