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Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum.
Lee DSM, Cardone KM, Zhang DY, Abramowitz S, DePaolo JS, Aragam KG, Biddinger K, Conery M, Dilitikas O, Hoffman-Andrews L, Judy RL, Khan A, Kulo I, Puckelwartz MJ, Reza N, Satterfield BA, Singhal P; Regeneron Genetics Center; Arany ZP, Cappola TP, Carruth E, Day SM, Do R, Haggarty CM, Joseph J, McNally E, Nadkarni G, Owens AT, Rader DJ, Ritchie MD, Sun Y, Voight BF, Levin MG, Damrauer SM. Lee DSM, et al. Among authors: sun y. medRxiv [Preprint]. 2023 Oct 2:2023.07.16.23292724. doi: 10.1101/2023.07.16.23292724. medRxiv. 2023. PMID: 37503172 Free PMC article. Preprint.
Design and Pilot Results from Million Veteran Program Return Of Actionable Genetic Results (MVP-ROAR) Study.
Vassy JL, Brunette CA, Yi T, Harrison A, Cardellino MP, Assimes TL, Christensen KD, Devineni P, Gaziano JM, Gong X, Hui Q, Knowles JW, Muralidhar S, Natarajan P, Pyarajan S, Sears MG, Shi Y, Sturm AC, Whitbourne SB, Sun YV, Danowski ME; Million Veteran Program. Vassy JL, et al. Among authors: sun yv. Am Heart J. 2024 May 16:S0002-8703(24)00115-7. doi: 10.1016/j.ahj.2024.04.021. Online ahead of print. Am Heart J. 2024. PMID: 38762090
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.
Rusu V, Hoch E, Mercader JM, Tenen DE, Gymrek M, Hartigan CR, DeRan M, von Grotthuss M, Fontanillas P, Spooner A, Guzman G, Deik AA, Pierce KA, Dennis C, Clish CB, Carr SA, Wagner BK, Schenone M, Ng MCY, Chen BH; MEDIA Consortium; SIGMA T2D Consortium; Centeno-Cruz F, Zerrweck C, Orozco L, Altshuler DM, Schreiber SL, Florez JC, Jacobs SBR, Lander ES. Rusu V, et al. Cell. 2017 Jun 29;170(1):199-212.e20. doi: 10.1016/j.cell.2017.06.011. Cell. 2017. PMID: 28666119 Free PMC article.
Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension.
Zhu X, Feng T, Tayo BO, Liang J, Young JH, Franceschini N, Smith JA, Yanek LR, Sun YV, Edwards TL, Chen W, Nalls M, Fox E, Sale M, Bottinger E, Rotimi C; COGENT BP Consortium; Liu Y, McKnight B, Liu K, Arnett DK, Chakravati A, Cooper RS, Redline S. Zhu X, et al. Among authors: sun yv. Am J Hum Genet. 2015 Jan 8;96(1):21-36. doi: 10.1016/j.ajhg.2014.11.011. Epub 2014 Dec 11. Am J Hum Genet. 2015. PMID: 25500260 Free PMC article.
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