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Increased human complement pathway regulatory protein gene dose is associated with increased endothelial expression and prolonged survival during ex-vivo perfusion of GTKO pig lungs with human blood.
Chaban R, McGrath G, Habibabady Z, Rosales I, Burdorf L, Ayares DL, Rybak E, Zhang T, Harris DG, Dahi S, Ali F, Parsell DM, Braileanu G, Cheng X, Sievert E, Phelps C, Azimzadeh AM, Pierson RN 3rd. Chaban R, et al. Among authors: harris dg. Xenotransplantation. 2023 Jul-Aug;30(4):e12812. doi: 10.1111/xen.12812. Epub 2023 Jul 28. Xenotransplantation. 2023. PMID: 37504492
Lung xenotransplantation: recent progress and current status.
Harris DG, Quinn KJ, Dahi S, Burdorf L, Azimzadeh AM, Pierson RN 3rd. Harris DG, et al. Xenotransplantation. 2014 Nov-Dec;21(6):496-506. doi: 10.1111/xen.12116. Epub 2014 Jul 5. Xenotransplantation. 2014. PMID: 25040467 Free PMC article. Review.
Platelet sequestration and activation during GalTKO.hCD46 pig lung perfusion by human blood is primarily mediated by GPIb, GPIIb/IIIa, and von Willebrand Factor.
Burdorf L, Riner A, Rybak E, Salles II, De Meyer SF, Shah A, Quinn KJ, Harris D, Zhang T, Parsell D, Ali F, Schwartz E, Kang E, Cheng X, Sievert E, Zhao Y, Braileanu G, Phelps CJ, Ayares DL, Deckmyn H, Pierson RN 3rd, Azimzadeh AM, Dandro A, Karavi K. Burdorf L, et al. Xenotransplantation. 2016 May;23(3):222-236. doi: 10.1111/xen.12236. Epub 2016 May 18. Xenotransplantation. 2016. PMID: 27188532 Free PMC article.
Selective CD28 Inhibition Modulates Alloimmunity and Cardiac Allograft Vasculopathy in Anti-CD154-Treated Monkeys.
Zhang T, Azimzadeh AM, Sun W, O'Neill NA, Sievert E, Bergbower E, Braileanu G, Burdorf L, Cheng X, Monahan T, Dahi S, Harris DG, Rybak E, Welty E, Kronfli A, Avon C, Pierson RN 3rd. Zhang T, et al. Among authors: harris dg. Transplantation. 2018 Mar;102(3):e90-e100. doi: 10.1097/TP.0000000000002044. Transplantation. 2018. PMID: 29319621 Free PMC article.
Thromboxane and histamine mediate PVR elevation during xenogeneic pig lung perfusion with human blood.
Burdorf L, Harris D, Dahi S, Laird C, Zhang T, Ali F, Shah A, Thompson M, Braileanu G, Cheng X, Sievert E, Schwartz E, Sendil S, Parsell DM, Redding E, Phelps CJ, Ayares DL, Azimzadeh AM, Pierson RN 3rd. Burdorf L, et al. Xenotransplantation. 2019 Mar;26(2):e12458. doi: 10.1111/xen.12458. Epub 2018 Sep 3. Xenotransplantation. 2019. PMID: 30175863 Free PMC article.
Pig-to-baboon lung xenotransplantation: Extended survival with targeted genetic modifications and pharmacologic treatments.
Burdorf L, Laird CT, Harris DG, Connolly MR, Habibabady Z, Redding E, O'Neill NA, Cimeno A, Parsell D, Phelps C, Ayares D, Azimzadeh AM, Pierson RN 3rd. Burdorf L, et al. Among authors: harris dg. Am J Transplant. 2022 Jan;22(1):28-45. doi: 10.1111/ajt.16809. Epub 2021 Sep 20. Am J Transplant. 2022. PMID: 34424601 Free PMC article.
Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood.
Burdorf L, Gao Z, Riner A, Sievert E, Harris DG, Kuravi KV, Morrill BH, Habibabady Z, Rybak E, Dahi S, Zhang T, Schwartz E, Kang E, Cheng X, Esmon CT, Phelps CJ, Ayares DL, Iii RNP, Azimzadeh AM. Burdorf L, et al. Among authors: harris dg. Xenotransplantation. 2023 Nov-Dec;30(6):e12828. doi: 10.1111/xen.12828. Epub 2023 Sep 28. Xenotransplantation. 2023. PMID: 37767640
81 results