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Increased human complement pathway regulatory protein gene dose is associated with increased endothelial expression and prolonged survival during ex-vivo perfusion of GTKO pig lungs with human blood.
Chaban R, McGrath G, Habibabady Z, Rosales I, Burdorf L, Ayares DL, Rybak E, Zhang T, Harris DG, Dahi S, Ali F, Parsell DM, Braileanu G, Cheng X, Sievert E, Phelps C, Azimzadeh AM, Pierson RN 3rd. Chaban R, et al. Among authors: rybak e. Xenotransplantation. 2023 Jul-Aug;30(4):e12812. doi: 10.1111/xen.12812. Epub 2023 Jul 28. Xenotransplantation. 2023. PMID: 37504492
Selective CD28 blockade attenuates acute and chronic rejection of murine cardiac allografts in a CTLA-4-dependent manner.
Zhang T, Fresnay S, Welty E, Sangrampurkar N, Rybak E, Zhou H, Cheng XF, Feng Q, Avon C, Laaris A, Whitters M, Nagelin AM, O'Hara RM Jr, Azimzadeh AM. Zhang T, et al. Among authors: rybak e. Am J Transplant. 2011 Aug;11(8):1599-609. doi: 10.1111/j.1600-6143.2011.03624.x. Epub 2011 Jul 12. Am J Transplant. 2011. PMID: 21749640 Free PMC article.
Pig-to-baboon liver xenoperfusion utilizing GalTKO.hCD46 pigs and glycoprotein Ib blockade.
LaMattina JC, Burdorf L, Zhang T, Rybak E, Cheng X, Munivenkatappa R, Salles II, Broos K, Sievert E, McCormick B, Decarlo M, Ayares D, Deckmyn H, Azimzadeh AM, Pierson RN 3rd, Barth RN. LaMattina JC, et al. Among authors: rybak e. Xenotransplantation. 2014 May-Jun;21(3):274-86. doi: 10.1111/xen.12093. Epub 2014 Mar 17. Xenotransplantation. 2014. PMID: 24628649 Free PMC article.
Expression of human CD46 modulates inflammation associated with GalTKO lung xenograft injury.
Burdorf L, Stoddard T, Zhang T, Rybak E, Riner A, Avon C, Laaris A, Cheng X, Sievert E, Braileanu G, Newton A, Phelps CJ, Ayares D, Azimzadeh AM, Pierson RN 3rd. Burdorf L, et al. Among authors: rybak e. Am J Transplant. 2014 May;14(5):1084-95. doi: 10.1111/ajt.12673. Epub 2014 Apr 2. Am J Transplant. 2014. PMID: 24698431 Free PMC article.
Platelet sequestration and activation during GalTKO.hCD46 pig lung perfusion by human blood is primarily mediated by GPIb, GPIIb/IIIa, and von Willebrand Factor.
Burdorf L, Riner A, Rybak E, Salles II, De Meyer SF, Shah A, Quinn KJ, Harris D, Zhang T, Parsell D, Ali F, Schwartz E, Kang E, Cheng X, Sievert E, Zhao Y, Braileanu G, Phelps CJ, Ayares DL, Deckmyn H, Pierson RN 3rd, Azimzadeh AM, Dandro A, Karavi K. Burdorf L, et al. Among authors: rybak e. Xenotransplantation. 2016 May;23(3):222-236. doi: 10.1111/xen.12236. Epub 2016 May 18. Xenotransplantation. 2016. PMID: 27188532 Free PMC article.
Preemptive CD20+ B cell Depletion Attenuates Cardiac Allograft Vasculopathy in CD154-Treated Monkeys.
Azimzadeh AM, Zhang T, Wu G, Kelishadi SS, Stoddard T, OʼNeill N, Nguyen BN, Welty E, Avon C, Higuchi M, Mitchell SL, Hershfeld A, Cheng XF, Kronfli A, Rybak E, Burdorf L, Pierson RN 3rd. Azimzadeh AM, et al. Among authors: rybak e. Transplantation. 2017 Jan;101(1):63-73. doi: 10.1097/TP.0000000000001258. Transplantation. 2017. PMID: 27362307 Free PMC article.
Selective CD28 Inhibition Modulates Alloimmunity and Cardiac Allograft Vasculopathy in Anti-CD154-Treated Monkeys.
Zhang T, Azimzadeh AM, Sun W, O'Neill NA, Sievert E, Bergbower E, Braileanu G, Burdorf L, Cheng X, Monahan T, Dahi S, Harris DG, Rybak E, Welty E, Kronfli A, Avon C, Pierson RN 3rd. Zhang T, et al. Among authors: rybak e. Transplantation. 2018 Mar;102(3):e90-e100. doi: 10.1097/TP.0000000000002044. Transplantation. 2018. PMID: 29319621 Free PMC article.
Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood.
Burdorf L, Gao Z, Riner A, Sievert E, Harris DG, Kuravi KV, Morrill BH, Habibabady Z, Rybak E, Dahi S, Zhang T, Schwartz E, Kang E, Cheng X, Esmon CT, Phelps CJ, Ayares DL, Iii RNP, Azimzadeh AM. Burdorf L, et al. Among authors: rybak e. Xenotransplantation. 2023 Nov-Dec;30(6):e12828. doi: 10.1111/xen.12828. Epub 2023 Sep 28. Xenotransplantation. 2023. PMID: 37767640
32 results