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Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease.
Mayer C, Nehring S, Kücken M, Repnik U, Seifert S, Sljukic A, Delpierre J, Morales-Navarrete H, Hinz S, Brosch M, Chung B, Karlsen T, Huch M, Kalaidzidis Y, Brusch L, Hampe J, Schafmayer C, Zerial M. Mayer C, et al. Among authors: zerial m. EMBO Rep. 2023 Sep 6;24(9):e57181. doi: 10.15252/embr.202357181. Epub 2023 Jul 31. EMBO Rep. 2023. PMID: 37522754 Free PMC article.
Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression.
Segovia-Miranda F, Morales-Navarrete H, Kücken M, Moser V, Seifert S, Repnik U, Rost F, Brosch M, Hendricks A, Hinz S, Röcken C, Lütjohann D, Kalaidzidis Y, Schafmayer C, Brusch L, Hampe J, Zerial M. Segovia-Miranda F, et al. Among authors: zerial m. Nat Med. 2019 Dec;25(12):1885-1893. doi: 10.1038/s41591-019-0660-7. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792455 Free PMC article.
Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads.
Belicova L, Repnik U, Delpierre J, Gralinska E, Seifert S, Valenzuela JI, Morales-Navarrete HA, Franke C, Räägel H, Shcherbinina E, Prikazchikova T, Koteliansky V, Vingron M, Kalaidzidis YL, Zatsepin T, Zerial M. Belicova L, et al. Among authors: zerial m. J Cell Biol. 2021 Oct 4;220(10):e202103003. doi: 10.1083/jcb.202103003. Epub 2021 Jul 30. J Cell Biol. 2021. PMID: 34328499 Free PMC article.
Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure.
Bebelman MP, Bovyn MJ, Mayer CM, Delpierre J, Naumann R, Martins NP, Honigmann A, Kalaidzidis Y, Haas PA, Zerial M. Bebelman MP, et al. Among authors: zerial m. J Cell Biol. 2023 Apr 3;222(4):e202208002. doi: 10.1083/jcb.202208002. Epub 2023 Jan 30. J Cell Biol. 2023. PMID: 36716168 Free PMC article.
A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule.
Meyer K, Ostrenko O, Bourantas G, Morales-Navarrete H, Porat-Shliom N, Segovia-Miranda F, Nonaka H, Ghaemi A, Verbavatz JM, Brusch L, Sbalzarini I, Kalaidzidis Y, Weigert R, Zerial M. Meyer K, et al. Among authors: zerial m. Cell Syst. 2017 Mar 22;4(3):277-290.e9. doi: 10.1016/j.cels.2017.02.008. Epub 2017 Mar 18. Cell Syst. 2017. PMID: 28330614 Free PMC article.
Liquid-crystal organization of liver tissue.
Morales-Navarrete H, Nonaka H, Scholich A, Segovia-Miranda F, de Back W, Meyer K, Bogorad RL, Koteliansky V, Brusch L, Kalaidzidis Y, Jülicher F, Friedrich BM, Zerial M. Morales-Navarrete H, et al. Among authors: zerial m. Elife. 2019 Jun 17;8:e44860. doi: 10.7554/eLife.44860. Elife. 2019. PMID: 31204997 Free PMC article.
Resilience of three-dimensional sinusoidal networks in liver tissue.
Karschau J, Scholich A, Wise J, Morales-Navarrete H, Kalaidzidis Y, Zerial M, Friedrich BM. Karschau J, et al. Among authors: zerial m. PLoS Comput Biol. 2020 Jun 29;16(6):e1007965. doi: 10.1371/journal.pcbi.1007965. eCollection 2020 Jun. PLoS Comput Biol. 2020. PMID: 32598356 Free PMC article.
Quantification of nematic cell polarity in three-dimensional tissues.
Scholich A, Syga S, Morales-Navarrete H, Segovia-Miranda F, Nonaka H, Meyer K, de Back W, Brusch L, Kalaidzidis Y, Zerial M, Jülicher F, Friedrich BM. Scholich A, et al. Among authors: zerial m. PLoS Comput Biol. 2020 Dec 10;16(12):e1008412. doi: 10.1371/journal.pcbi.1008412. eCollection 2020 Dec. PLoS Comput Biol. 2020. PMID: 33301446 Free PMC article.
197 results