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Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis.
Liu W, Yalcinkaya M, Maestre IF, Olszewska M, Ampomah PB, Heimlich JB, Wang R, Vela PS, Xiao T, Bick AG, Levine R, Papapetrou EP, Libby P, Tabas I, Wang N, Tall AR. Liu W, et al. Among authors: libby p. Nat Cardiovasc Res. 2023 Jun;2(6):572-586. doi: 10.1038/s44161-023-00281-3. Epub 2023 Jun 8. Nat Cardiovasc Res. 2023. PMID: 37539077 Free PMC article.
Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, Welch CL, Tall AR. Sun Y, et al. Among authors: libby p. Circ Res. 2009 Feb 27;104(4):455-65. doi: 10.1161/CIRCRESAHA.108.182568. Epub 2009 Jan 2. Circ Res. 2009. PMID: 19122179 Free PMC article.
Inflammation and plaque vulnerability.
Hansson GK, Libby P, Tabas I. Hansson GK, et al. Among authors: libby p. J Intern Med. 2015 Nov;278(5):483-93. doi: 10.1111/joim.12406. Epub 2015 Aug 11. J Intern Med. 2015. PMID: 26260307 Free PMC article. Review.
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.
Jaiswal S, Natarajan P, Silver AJ, Gibson CJ, Bick AG, Shvartz E, McConkey M, Gupta N, Gabriel S, Ardissino D, Baber U, Mehran R, Fuster V, Danesh J, Frossard P, Saleheen D, Melander O, Sukhova GK, Neuberg D, Libby P, Kathiresan S, Ebert BL. Jaiswal S, et al. Among authors: libby p. N Engl J Med. 2017 Jul 13;377(2):111-121. doi: 10.1056/NEJMoa1701719. Epub 2017 Jun 21. N Engl J Med. 2017. PMID: 28636844 Free PMC article.
941 results