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Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis.
Liu W, Yalcinkaya M, Maestre IF, Olszewska M, Ampomah PB, Heimlich JB, Wang R, Vela PS, Xiao T, Bick AG, Levine R, Papapetrou EP, Libby P, Tabas I, Wang N, Tall AR. Liu W, et al. Among authors: papapetrou ep. Nat Cardiovasc Res. 2023 Jun;2(6):572-586. doi: 10.1038/s44161-023-00281-3. Epub 2023 Jun 8. Nat Cardiovasc Res. 2023. PMID: 37539077 Free PMC article.
The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells.
Perna F, Vu LP, Themeli M, Kriks S, Hoya-Arias R, Khanin R, Hricik T, Mansilla-Soto J, Papapetrou EP, Levine RL, Studer L, Sadelain M, Nimer SD. Perna F, et al. Among authors: papapetrou ep. Stem Cell Reports. 2015 Apr 14;4(4):658-69. doi: 10.1016/j.stemcr.2015.02.003. Epub 2015 Mar 5. Stem Cell Reports. 2015. PMID: 25754204 Free PMC article.
Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.
Kotini AG, Chang CJ, Chow A, Yuan H, Ho TC, Wang T, Vora S, Solovyov A, Husser C, Olszewska M, Teruya-Feldstein J, Perumal D, Klimek VM, Spyridonidis A, Rampal RK, Silverman L, Reddy EP, Papaemmanuil E, Parekh S, Greenbaum BD, Leslie CS, Kharas MG, Papapetrou EP. Kotini AG, et al. Among authors: papapetrou ep. Cell Stem Cell. 2017 Mar 2;20(3):315-328.e7. doi: 10.1016/j.stem.2017.01.009. Epub 2017 Feb 16. Cell Stem Cell. 2017. PMID: 28215825 Free PMC article.
Dissecting the Contributions of Cooperating Gene Mutations to Cancer Phenotypes and Drug Responses with Patient-Derived iPSCs.
Chang CJ, Kotini AG, Olszewska M, Georgomanoli M, Teruya-Feldstein J, Sperber H, Sanchez R, DeVita R, Martins TJ, Abdel-Wahab O, Bradley RK, Papapetrou EP. Chang CJ, et al. Among authors: papapetrou ep. Stem Cell Reports. 2018 May 8;10(5):1610-1624. doi: 10.1016/j.stemcr.2018.03.020. Epub 2018 Apr 19. Stem Cell Reports. 2018. PMID: 29681544 Free PMC article.
The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.
Fidler TP, Xue C, Yalcinkaya M, Hardaway B, Abramowicz S, Xiao T, Liu W, Thomas DG, Hajebrahimi MA, Pircher J, Silvestre-Roig C, Kotini AG, Luchsinger LL, Wei Y, Westerterp M, Snoeck HW, Papapetrou EP, Schulz C, Massberg S, Soehnlein O, Ebert B, Levine RL, Reilly MP, Libby P, Wang N, Tall AR. Fidler TP, et al. Among authors: papapetrou ep. Nature. 2021 Apr;592(7853):296-301. doi: 10.1038/s41586-021-03341-5. Epub 2021 Mar 17. Nature. 2021. PMID: 33731931 Free PMC article.
Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency.
Dou H, Kotini A, Liu W, Fidler T, Endo-Umeda K, Sun X, Olszewska M, Xiao T, Abramowicz S, Yalcinkaya M, Hardaway B, Tsimikas S, Que X, Bick A, Emdin C, Natarajan P, Papapetrou EP, Witztum JL, Wang N, Tall AR. Dou H, et al. Among authors: papapetrou ep. Circulation. 2021 Dec 14;144(24):1940-1954. doi: 10.1161/CIRCULATIONAHA.121.056414. Epub 2021 Nov 30. Circulation. 2021. PMID: 34846914 Free PMC article.
Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein.
Yalcinkaya M, Liu W, Islam MN, Kotini AG, Gusarova GA, Fidler TP, Papapetrou EP, Bhattacharya J, Wang N, Tall AR. Yalcinkaya M, et al. Among authors: papapetrou ep. Sci Rep. 2021 Dec 24;11(1):24432. doi: 10.1038/s41598-021-04133-7. Sci Rep. 2021. PMID: 34952919 Free PMC article.
Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1-mutant HSPCs.
Asimomitis G, Deslauriers AG, Kotini AG, Bernard E, Esposito D, Olszewska M, Spyrou N, Arango Ossa J, Mortera-Blanco T, Koche R, Nannya Y, Malcovati L, Ogawa S, Cazzola M, Aaronson SA, Hellström-Lindberg E, Papaemmanuil E, Papapetrou EP. Asimomitis G, et al. Among authors: papapetrou ep. Blood Adv. 2022 May 24;6(10):2992-3005. doi: 10.1182/bloodadvances.2021006325. Blood Adv. 2022. PMID: 35042235 Free PMC article.
Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia.
Kotini AG, Carcamo S, Cruz-Rodriguez N, Olszewska M, Wang T, Demircioglu D, Chang CJ, Bernard E, Chao MP, Majeti R, Luo H, Kharas MG, Hasson D, Papapetrou EP. Kotini AG, et al. Among authors: papapetrou ep. Blood Cancer Discov. 2023 Jul 5;4(4):318-335. doi: 10.1158/2643-3230.BCD-22-0167. Blood Cancer Discov. 2023. PMID: 37067914 Free PMC article.
66 results