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Severity of GNAO1-Related Disorder Correlates with Changes in G-Protein Function.
Domínguez-Carral J, Ludlam WG, Junyent Segarra M, Fornaguera Marti M, Balsells S, Muchart J, Čokolić Petrović D, Espinoza I, Ortigoza-Escobar JD, Martemyanov KA; GNAO1-Study Group. Domínguez-Carral J, et al. Among authors: martemyanov ka. Ann Neurol. 2023 Nov;94(5):987-1004. doi: 10.1002/ana.26758. Epub 2023 Aug 31. Ann Neurol. 2023. PMID: 37548038
Diverse faces of GNAO1: mild forms in epilepsy and autism.
Ludlam WG, Soliani L, Domínguez-Carral J, Cordelli DM, Marchiani V, Gorría-Redondo N, Aguilera-Albesa S, Martemyanov KA, Ortigoza-Escobar JD. Ludlam WG, et al. Among authors: martemyanov ka. J Neurol. 2024 May 10. doi: 10.1007/s00415-024-12418-w. Online ahead of print. J Neurol. 2024. PMID: 38724739 No abstract available.
Rules and mechanisms governing G protein coupling selectivity of GPCRs.
Masuho I, Kise R, Gainza P, Von Moo E, Li X, Tany R, Wakasugi-Masuho H, Correia BE, Martemyanov KA. Masuho I, et al. Among authors: martemyanov ka. Cell Rep. 2023 Oct 31;42(10):113173. doi: 10.1016/j.celrep.2023.113173. Epub 2023 Sep 23. Cell Rep. 2023. PMID: 37742189 Free PMC article.
Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review.
Papapetropoulos A, Topouzis S, Alexander SPH, Cortese-Krott M, Kendall DA, Martemyanov KA, Mauro C, Nagercoil N, Panettieri RA Jr, Patel HH, Schulz R, Stefanska B, Stephens GJ, Teixeira MM, Vergnolle N, Wang X, Ferdinandy P. Papapetropoulos A, et al. Among authors: martemyanov ka. Br J Pharmacol. 2024 Jun;181(11):1553-1575. doi: 10.1111/bph.16337. Epub 2024 Mar 22. Br J Pharmacol. 2024. PMID: 38519837 Review.
Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Patil DN, Pantalone S, Cao Y, Laboute T, Novick SJ, Singh S, Savino S, Faravelli S, Magnani F, Griffin PR, Singh AK, Forneris F, Martemyanov KA. Patil DN, et al. Among authors: martemyanov ka. Sci Signal. 2023 Jul 25;16(795):eadd9539. doi: 10.1126/scisignal.add9539. Epub 2023 Jul 25. Sci Signal. 2023. PMID: 37490546 Free PMC article.
Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR.
Laboute T, Zucca S, Holcomb M, Patil DN, Garza C, Wheatley BA, Roy RN, Forli S, Martemyanov KA. Laboute T, et al. Among authors: martemyanov ka. Science. 2023 Mar 31;379(6639):1352-1358. doi: 10.1126/science.add7150. Epub 2023 Mar 30. Science. 2023. PMID: 36996198 Free PMC article.
Middle-Down Mass Spectrometry Reveals Activity-Modifying Phosphorylation Barcode in a Class C G Protein-Coupled Receptor.
Ives AN, Dunn HA, Afsari HS, Seckler HDS, Foroutan MJ, Chavez E, Melani RD, Fellers RT, LeDuc RD, Thomas PM, Martemyanov KA, Kelleher NL, Vafabakhsh R. Ives AN, et al. Among authors: martemyanov ka. J Am Chem Soc. 2022 Dec 21;144(50):23104-23114. doi: 10.1021/jacs.2c10697. Epub 2022 Dec 7. J Am Chem Soc. 2022. PMID: 36475650 Free PMC article.
156 results