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Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms.
Nat Cancer. 2023 Aug;4(8):1193-1209. doi: 10.1038/s43018-023-00607-x. Epub 2023 Aug 7.
Nat Cancer. 2023.
PMID: 37550517
Free PMC article.
Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm.
Rai S, Grockowiak E, Hansen N, Luque Paz D, Stoll CB, Hao-Shen H, Mild-Schneider G, Dirnhofer S, Farady CJ, Méndez-Ferrer S, Skoda RC.
Rai S, et al. Among authors: grockowiak e.
Nat Commun. 2022 Sep 13;13(1):5346. doi: 10.1038/s41467-022-32927-4.
Nat Commun. 2022.
PMID: 36100613
Free PMC article.
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Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression.
Valet C, Magnen M, Qiu L, Cleary SJ, Wang KM, Ranucci S, Grockowiak E, Boudra R, Conrad C, Seo Y, Calabrese DR, Greenland JR, Leavitt AD, Passegué E, Méndez-Ferrer S, Swirski FK, Looney MR.
Valet C, et al. Among authors: grockowiak e.
J Clin Invest. 2022 Apr 1;132(7):e153920. doi: 10.1172/JCI153920.
J Clin Invest. 2022.
PMID: 35192546
Free PMC article.
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IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells.
Rai S, Zhang Y, Grockowiak E, Kimmerlin Q, Hansen N, Stoll CB, Usart M, Luque Paz D, Hao-Shen H, Zhu Y, Roux J, Bader MS, Dirnhofer S, Farady CJ, Schroeder T, Méndez-Ferrer S, Skoda RC.
Rai S, et al. Among authors: grockowiak e.
Blood Adv. 2024 Mar 12;8(5):1234-1249. doi: 10.1182/bloodadvances.2023011338.
Blood Adv. 2024.
PMID: 38207211
Free PMC article.
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The quiescent fraction of chronic myeloid leukemic stem cells depends on BMPR1B, Stat3 and BMP4-niche signals to persist in patients in remission.
Jeanpierre S, Arizkane K, Thongjuea S, Grockowiak E, Geistlich K, Barral L, Voeltzel T, Guillemin A, Gonin-Giraud S, Gandrillon O, Nicolini FE, Mead AJ, Maguer-Satta V, Lefort S.
Jeanpierre S, et al. Among authors: grockowiak e.
Haematologica. 2021 Jan 1;106(1):111-122. doi: 10.3324/haematol.2019.232793.
Haematologica. 2021.
PMID: 32001529
Free PMC article.
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Immature CML cells implement a BMP autocrine loop to escape TKI treatment.
Grockowiak E, Laperrousaz B, Jeanpierre S, Voeltzel T, Guyot B, Gobert S, Nicolini FE, Maguer-Satta V.
Grockowiak E, et al.
Blood. 2017 Dec 28;130(26):2860-2871. doi: 10.1182/blood-2017-08-801019. Epub 2017 Nov 14.
Blood. 2017.
PMID: 29138221
Free article.
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Stem cell manipulation, gene therapy and the risk of cancer stem cell emergence.
Clément F, Grockowiak E, Zylbersztejn F, Fossard G, Gobert S, Maguer-Satta V.
Clément F, et al. Among authors: grockowiak e.
Stem Cell Investig. 2017 Jul 25;4:67. doi: 10.21037/sci.2017.07.03. eCollection 2017.
Stem Cell Investig. 2017.
PMID: 28815178
Free PMC article.
Review.
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T315I+ tyrosine-kinase independent CML cells resistance.
Nicolini FE, Grockowiak E, Maguer-Satta V.
Nicolini FE, et al. Among authors: grockowiak e.
Oncotarget. 2017 Jul 4;8(27):43600-43601. doi: 10.18632/oncotarget.18573.
Oncotarget. 2017.
PMID: 28642447
Free PMC article.
No abstract available.
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