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Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms.
Nat Cancer. 2023 Aug;4(8):1193-1209. doi: 10.1038/s43018-023-00607-x. Epub 2023 Aug 7.
Nat Cancer. 2023.
PMID: 37550517
Free PMC article.
Heterogeneous run-and-tumble motion accounts for transient non-Gaussian super-diffusion in haematopoietic multi-potent progenitor cells.
Partridge B, Gonzalez Anton S, Khorshed R, Adams G, Pospori C, Lo Celso C, Lee CF.
Partridge B, et al.
PLoS One. 2022 Sep 13;17(9):e0272587. doi: 10.1371/journal.pone.0272587. eCollection 2022.
PLoS One. 2022.
PMID: 36099240
Free PMC article.
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T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.
Hawkins ED, Duarte D, Akinduro O, Khorshed RA, Passaro D, Nowicka M, Straszkowski L, Scott MK, Rothery S, Ruivo N, Foster K, Waibel M, Johnstone RW, Harrison SJ, Westerman DA, Quach H, Gribben J, Robinson MD, Purton LE, Bonnet D, Lo Celso C.
Hawkins ED, et al. Among authors: khorshed ra.
Nature. 2016 Oct 27;538(7626):518-522. doi: 10.1038/nature19801. Epub 2016 Oct 17.
Nature. 2016.
PMID: 27750279
Free PMC article.
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Imaging methods used to study mouse and human HSC niches: Current and emerging technologies.
Tjin G, Flores-Figueroa E, Duarte D, Straszkowski L, Scott M, Khorshed RA, Purton LE, Lo Celso C.
Tjin G, et al. Among authors: khorshed ra.
Bone. 2019 Feb;119:19-35. doi: 10.1016/j.bone.2018.04.022. Epub 2018 Apr 25.
Bone. 2019.
PMID: 29704697
Review.
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Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.
Duarte D, Hawkins ED, Akinduro O, Ang H, De Filippo K, Kong IY, Haltalli M, Ruivo N, Straszkowski L, Vervoort SJ, McLean C, Weber TS, Khorshed R, Pirillo C, Wei A, Ramasamy SK, Kusumbe AP, Duffy K, Adams RH, Purton LE, Carlin LM, Lo Celso C.
Duarte D, et al.
Cell Stem Cell. 2018 Jan 4;22(1):64-77.e6. doi: 10.1016/j.stem.2017.11.006. Epub 2017 Dec 21.
Cell Stem Cell. 2018.
PMID: 29276143
Free PMC article.
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Automated Identification and Localization of Hematopoietic Stem Cells in 3D Intravital Microscopy Data.
Khorshed RA, Hawkins ED, Duarte D, Scott MK, Akinduro OA, Rashidi NM, Spitaler M, Lo Celso C.
Khorshed RA, et al.
Stem Cell Reports. 2015 Jul 14;5(1):139-53. doi: 10.1016/j.stemcr.2015.05.017. Epub 2015 Jun 25.
Stem Cell Reports. 2015.
PMID: 26120058
Free PMC article.
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Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection.
MacLean AL, Smith MA, Liepe J, Sim A, Khorshed R, Rashidi NM, Scherf N, Krinner A, Roeder I, Lo Celso C, Stumpf MPH.
MacLean AL, et al.
Stem Cells. 2017 Nov;35(11):2292-2304. doi: 10.1002/stem.2692. Epub 2017 Sep 24.
Stem Cells. 2017.
PMID: 28833970
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Redirection to the bone marrow improves T cell persistence and antitumor functions.
Khan AB, Carpenter B, Santos E Sousa P, Pospori C, Khorshed R, Griffin J, Velica P, Zech M, Ghorashian S, Forrest C, Thomas S, Gonzalez Anton S, Ahmadi M, Holler A, Flutter B, Ramirez-Ortiz Z, Means TK, Bennett CL, Stauss H, Morris E, Lo Celso C, Chakraverty R.
Khan AB, et al.
J Clin Invest. 2018 May 1;128(5):2010-2024. doi: 10.1172/JCI97454. Epub 2018 Apr 9.
J Clin Invest. 2018.
PMID: 29485974
Free PMC article.
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