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Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma.
Flanagan KC, Earls J, Schillebeeckx I, Hiken J, Wellinghoff RL, LaFranzo NA, Bradley ZS, Babbitt J, Westra WH, Hsu R, Nadauld L, Mcleod H, Firth SD, Sharp B, Fuller J, Vavinskaya V, Sutton L, Deichaite I, Bailey SD, Sandulache VC, Rendo MJ, Macdonald OK, Welaya K, Wade JL 3rd, Pippas AW, Slim J, Bank B, Saccaro SJ, Sui X, Akhtar A, Balaraman S, Kossman SE, Sonnier SA, Shenkenberg TD, Alexander WL, Price KA, Bane CL, Ley J, Messina DN, Glasscock JI, Cohen EEW, Adkins DR, Duncavage EJ. Flanagan KC, et al. J Cancer Res Clin Oncol. 2023 Nov;149(15):14125-14136. doi: 10.1007/s00432-023-05205-z. Epub 2023 Aug 8. J Cancer Res Clin Oncol. 2023. PMID: 37552307 Free PMC article.
Analytical Performance of an Immunoprofiling Assay Based on RNA Models.
Schillebeeckx I, Armstrong JR, Forys JT, Hiken J, Earls J, Flanagan KC, Cui T, Glasscock JI, Messina DN, Duncavage EJ. Schillebeeckx I, et al. Among authors: flanagan kc. J Mol Diagn. 2020 Apr;22(4):555-570. doi: 10.1016/j.jmoldx.2020.01.009. Epub 2020 Feb 7. J Mol Diagn. 2020. PMID: 32036085 Free article.
T cell subtype profiling measures exhaustion and predicts anti-PD-1 response.
Schillebeeckx I, Earls J, Flanagan KC, Hiken J, Bode A, Armstrong JR, Messina DN, Adkins D, Ley J, Alborelli I, Jermann P, Glasscock JI. Schillebeeckx I, et al. Among authors: flanagan kc. Sci Rep. 2022 Jan 25;12(1):1342. doi: 10.1038/s41598-022-05474-7. Sci Rep. 2022. PMID: 35079117 Free PMC article.
Predictive Immune Modeling of Solid Tumors.
LaFranzo NA, Flanagan KC, Quintanilha D. LaFranzo NA, et al. Among authors: flanagan kc. J Vis Exp. 2020 Feb 25;(156). doi: 10.3791/60645. J Vis Exp. 2020. PMID: 32176206
Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells.
Goff PH, Riolobos L, LaFleur BJ, Spraker MB, Seo YD, Smythe KS, Campbell JS, Pierce RH, Zhang Y, He Q, Kim EY, Schaub SK, Kane GM, Mantilla JG, Chen EY, Ricciotti R, Thompson MJ, Cranmer LD, Wagner MJ, Loggers ET, Jones RL, Murphy E, Blumenschein WM, McClanahan TK, Earls J, Flanagan KC, LaFranzo NA, Kim TS, Pollack SM. Goff PH, et al. Among authors: flanagan kc. Clin Cancer Res. 2022 Apr 14;28(8):1701-1711. doi: 10.1158/1078-0432.CCR-21-4239. Clin Cancer Res. 2022. PMID: 35115306 Free PMC article.
CD4+ T cell and M2 macrophage infiltration predict dedifferentiated liposarcoma patient outcomes.
Schroeder BA, LaFranzo NA, LaFleur BJ, Gittelman RM, Vignali M, Zhang S, Flanagan KC, Rytlewski J, Riolobos L, Schulte BC, Kim TS, Chen E, Smythe KS, Wagner MJ, Mantilla JG, Campbell JS, Pierce RH, Jones RL, Cranmer LD, Pollack SM. Schroeder BA, et al. Among authors: flanagan kc. J Immunother Cancer. 2021 Aug;9(8):e002812. doi: 10.1136/jitc-2021-002812. J Immunother Cancer. 2021. PMID: 34465597 Free PMC article.
Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss.
Murali B, Ren Q, Luo X, Faget DV, Wang C, Johnson RM, Gruosso T, Flanagan KC, Fu Y, Leahy K, Alspach E, Su X, Ross MH, Burnette B, Weilbaecher KN, Park M, Mbalaviele G, Monahan JB, Stewart SA. Murali B, et al. Among authors: flanagan kc. Cancer Res. 2018 Oct 1;78(19):5618-5630. doi: 10.1158/0008-5472.CAN-18-0234. Epub 2018 Aug 9. Cancer Res. 2018. PMID: 30093561 Free PMC article.
p38MAPK plays a crucial role in stromal-mediated tumorigenesis.
Alspach E, Flanagan KC, Luo X, Ruhland MK, Huang H, Pazolli E, Donlin MJ, Marsh T, Piwnica-Worms D, Monahan J, Novack DV, McAllister SS, Stewart SA. Alspach E, et al. Among authors: flanagan kc. Cancer Discov. 2014 Jun;4(6):716-29. doi: 10.1158/2159-8290.CD-13-0743. Epub 2014 Mar 26. Cancer Discov. 2014. PMID: 24670723 Free PMC article.
14 results