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CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.
Chen D, Varanasi SK, Hara T, Traina K, Sun M, McDonald B, Farsakoglu Y, Clanton J, Xu S, Garcia-Rivera L, Mann TH, Du V, Chung HK, Xu Z, Tripple V, Casillas E, Ma S, O'Connor C, Yang Q, Zheng Y, Hunter T, Lemke G, Kaech SM. Chen D, et al. Among authors: kaech sm. Immunity. 2023 Sep 12;56(9):2086-2104.e8. doi: 10.1016/j.immuni.2023.07.015. Epub 2023 Aug 11. Immunity. 2023. PMID: 37572655
CD8+ T cells in the cancer-immunity cycle.
Giles JR, Globig AM, Kaech SM, Wherry EJ. Giles JR, et al. Among authors: kaech sm. Immunity. 2023 Oct 10;56(10):2231-2253. doi: 10.1016/j.immuni.2023.09.005. Immunity. 2023. PMID: 37820583 Review.
1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development.
Wang T, Wang Z, de Fabritus L, Tao J, Saied EM, Lee HJ, Ramazanov BR, Jackson B, Burkhardt D, Parker M, Gleinich AS, Wang Z, Seo DE, Zhou T, Xu S, Alecu I, Azadi P, Arenz C, Hornemann T, Krishnaswamy S, van de Pavert SA, Kaech SM, Ivanova NB, Santori FR. Wang T, et al. Among authors: kaech sm. Dev Cell. 2021 Nov 22;56(22):3128-3145.e15. doi: 10.1016/j.devcel.2021.10.018. Epub 2021 Nov 10. Dev Cell. 2021. PMID: 34762852 Free PMC article.
Eicosanoids in the pancreatic tumor microenvironment - a multicellular, multifaceted progression.
Gubbala VB, Jytosana N, Trinh VQ, Maurer HC, Naeem RF, Lytle NK, Ma Z, Zhao S, Lin W, Han H, Shi Y, Hunter T, Singh PK, Olive KP, Tan MCB, Kaech SM, Wahl GM, DelGiorno KE. Gubbala VB, et al. Among authors: kaech sm. Gastro Hep Adv. 2022;1(4):682-697. doi: 10.1016/j.gastha.2022.02.007. Epub 2022 Jun 11. Gastro Hep Adv. 2022. PMID: 36277993 Free PMC article.
ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity.
Maxwell MB, Hom-Tedla MS, Yi J, Li S, Rivera SA, Yu J, Burns MJ, McRae HM, Stevenson BT, Coakley KE, Ho J, Gastelum KB, Bell JC, Jones AC, Eskander RN, Dykhuizen EC, Shadel GS, Kaech SM, Hargreaves DC. Maxwell MB, et al. Among authors: kaech sm. Cell. 2024 May 9:S0092-8674(24)00451-3. doi: 10.1016/j.cell.2024.04.025. Online ahead of print. Cell. 2024. PMID: 38754421
Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2.
DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM. DelGiorno KE, et al. Among authors: kaech sm. Gastroenterology. 2020 Nov;159(5):1866-1881.e8. doi: 10.1053/j.gastro.2020.07.037. Epub 2020 Jul 24. Gastroenterology. 2020. PMID: 32717220 Free PMC article.
163 results