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Ethynylflavones, highly potent, and selective inhibitors of cytochrome P450 1A1.
Goyal N, Liu J, Lovings L, Dupart P, Taylor S, Bellow S, Mensah L, McClain E, Dotson B, Sridhar J, Zhang X, Zhao M, Foroozesh M. Goyal N, et al. Chem Res Toxicol. 2014 Aug 18;27(8):1431-9. doi: 10.1021/tx5001865. Epub 2014 Jul 29. Chem Res Toxicol. 2014. PMID: 25033111 Free PMC article.
A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2.
Liu J, Pham PT, Skripnikova EV, Zheng S, Lovings LJ, Wang Y, Goyal N, Bellow SM, Mensah LM, Chatters AJ, Bratton MR, Wiese TE, Zhao M, Wang G, Foroozesh M. Liu J, et al. Among authors: goyal n. J Med Chem. 2015 Aug 27;58(16):6481-93. doi: 10.1021/acs.jmedchem.5b00494. Epub 2015 Aug 10. J Med Chem. 2015. PMID: 26222195 Free PMC article.
Ethyl 2-[2-(4-oxo-4H-chromen-2-yl)phenoxy]acetate.
Goyal N, Do C, Donahue JP, Mague JT, Foroozesh M. Goyal N, et al. IUCrdata. 2018 Jul;3(7):x180993. doi: 10.1107/S2414314618009938. IUCrdata. 2018. PMID: 30984887 Free PMC article.
Coumarins and P450s, Studies Reported to-Date.
Foroozesh M, Sridhar J, Goyal N, Liu J. Foroozesh M, et al. Among authors: goyal n. Molecules. 2019 Apr 24;24(8):1620. doi: 10.3390/molecules24081620. Molecules. 2019. PMID: 31022888 Free PMC article. Review.
A dibenzofuran derivative: 2-(pentyloxy)dibenzo[b,d]furan.
Goyal N, Donahue JP, Do C, Perry T, Bongay-Williams K, Foroozesh M. Goyal N, et al. IUCrdata. 2018 Sep;3(9):x181306. doi: 10.1107/S2414314618013068. IUCrdata. 2018. PMID: 31363506 Free PMC article.
1,346 results