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Protein-metabolite association studies identify novel proteomic determinants of metabolite levels in human plasma.
Benson MD, Eisman AS, Tahir UA, Katz DH, Deng S, Ngo D, Robbins JM, Hofmann A, Shi X, Zheng S, Keyes M, Yu Z, Gao Y, Farrell L, Shen D, Chen ZZ, Cruz DE, Sims M, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Jain D, Yang Q; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Sarkar IN, Natarajan P, Gerszten RE. Benson MD, et al. Among authors: gerszten re. Cell Metab. 2023 Sep 5;35(9):1646-1660.e3. doi: 10.1016/j.cmet.2023.07.012. Epub 2023 Aug 14. Cell Metab. 2023. PMID: 37582364
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury.
Lewis GD, Wei R, Liu E, Yang E, Shi X, Martinovic M, Farrell L, Asnani A, Cyrille M, Ramanathan A, Shaham O, Berriz G, Lowry PA, Palacios IF, Taşan M, Roth FP, Min J, Baumgartner C, Keshishian H, Addona T, Mootha VK, Rosenzweig A, Carr SA, Fifer MA, Sabatine MS, Gerszten RE. Lewis GD, et al. Among authors: gerszten re. J Clin Invest. 2008 Oct;118(10):3503-12. doi: 10.1172/JCI35111. J Clin Invest. 2008. PMID: 18769631 Free PMC article. Clinical Trial.
Interpreting metabolomic profiles using unbiased pathway models.
Deo RC, Hunter L, Lewis GD, Pare G, Vasan RS, Chasman D, Wang TJ, Gerszten RE, Roth FP. Deo RC, et al. Among authors: gerszten re. PLoS Comput Biol. 2010 Feb 26;6(2):e1000692. doi: 10.1371/journal.pcbi.1000692. PLoS Comput Biol. 2010. PMID: 20195502 Free PMC article.
Metabolite profiling identifies markers of uremia.
Rhee EP, Souza A, Farrell L, Pollak MR, Lewis GD, Steele DJ, Thadhani R, Clish CB, Greka A, Gerszten RE. Rhee EP, et al. Among authors: gerszten re. J Am Soc Nephrol. 2010 Jun;21(6):1041-1051. doi: 10.1681/ASN.2009111132. Epub 2010 Apr 8. J Am Soc Nephrol. 2010. PMID: 20378825 Free PMC article.
Metabolic signatures of exercise in human plasma.
Lewis GD, Farrell L, Wood MJ, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, Sabatine MS, Clish CB, Gerszten RE. Lewis GD, et al. Among authors: gerszten re. Sci Transl Med. 2010 May 26;2(33):33ra37. doi: 10.1126/scitranslmed.3001006. Sci Transl Med. 2010. PMID: 20505214 Free PMC article.
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.
Rhee EP, Cheng S, Larson MG, Walford GA, Lewis GD, McCabe E, Yang E, Farrell L, Fox CS, O'Donnell CJ, Carr SA, Vasan RS, Florez JC, Clish CB, Wang TJ, Gerszten RE. Rhee EP, et al. Among authors: gerszten re. J Clin Invest. 2011 Apr;121(4):1402-11. doi: 10.1172/JCI44442. Epub 2011 Mar 14. J Clin Invest. 2011. PMID: 21403394 Free PMC article.
292 results