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Archival single-cell genomics reveals persistent subclones during DCIS progression.
Wang K, Kumar T, Wang J, Minussi DC, Sei E, Li J, Tran TM, Thennavan A, Hu M, Casasent AK, Xiao Z, Bai S, Yang L, King LM, Shah V, Kristel P, van der Borden CL, Marks JR, Zhao Y, Zurita AJ, Aparicio A, Chapin B, Ye J, Zhang J, Gibbons DL; Grand Challenge PRECISION Consortium; Sawyer E, Thompson AM, Futreal A, Hwang ES, Wesseling J, Lips EH, Navin NE. Wang K, et al. Among authors: wesseling j. Cell. 2023 Aug 31;186(18):3968-3982.e15. doi: 10.1016/j.cell.2023.07.024. Epub 2023 Aug 15. Cell. 2023. PMID: 37586362
Comprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk.
Almekinders MM, Bismeijer T, Kumar T, Yang F, Thijssen B, van der Linden R, van Rooijen C, Vonk S, Sun B, Parra Cuentas ER, Wistuba II, Krishnamurthy S, Visser LL, Seignette IM, Hofland I, Sanders J, Broeks A, Love JK, Menegaz B, Wessels L, Thompson AM, de Visser KE, Hooijberg E, Lips E, Futreal A, Wesseling J; Grand Challenge PRECISION Consortium. Almekinders MM, et al. Among authors: wesseling j. Br J Cancer. 2022 Oct;127(7):1201-1213. doi: 10.1038/s41416-022-01888-2. Epub 2022 Jun 29. Br J Cancer. 2022. PMID: 35768550 Free PMC article.
Artificial intelligence-based morphometric signature to identify ductal carcinoma in situ with low risk of progression to invasive breast cancer.
Sobral-Leite M, Castillo S, Vonk S, Melillo X, Lam N, de Bruijn B, Hagos Y, Sanders J, Almekinders M, Visser L, Groen E, Kristel P, Ercan C, Azarang L, Yuan Y; Grand Challenge PRECISION Consortium; Menezes R, Lips E, Wesseling J. Sobral-Leite M, et al. Among authors: wesseling j. Res Sq [Preprint]. 2023 Dec 13:rs.3.rs-3639521. doi: 10.21203/rs.3.rs-3639521/v1. Res Sq. 2023. PMID: 38168198 Free PMC article. Preprint.
Causality and functional relevance of BRCA1 and BRCA2 pathogenic variants in non-high-grade serous ovarian carcinomas.
Kramer C, Lanjouw L, Ruano D, Ter Elst A, Santandrea G, Solleveld-Westerink N, Werner N, van der Hout AH, de Kroon CD, van Wezel T, Berger L, Jalving M, Wesseling J, Smit V, de Bock GH, van Asperen CJ, Mourits M, Vreeswijk M, Bart J, Bosse T. Kramer C, et al. Among authors: wesseling j. J Pathol. 2024 Feb;262(2):137-146. doi: 10.1002/path.6218. Epub 2023 Oct 18. J Pathol. 2024. PMID: 37850614
Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts.
Hutten SJ, Messal HA, Lips EH, Sheinman M, Ciwinska M, Braams E, van der Borden C, Kristel P, Stoffers S, Wessels LF; Grand Challenge PRECISION Consortium; Jonkers J, van Rheenen J, Wesseling J, Scheele CL. Hutten SJ, et al. Among authors: wesseling j. J Pathol. 2024 May 23. doi: 10.1002/path.6289. Online ahead of print. J Pathol. 2024. PMID: 38779852
Outdoor air pollution as a risk factor for testing positive for SARS-CoV-2: A nationwide test-negative case-control study in the Netherlands.
Simões M, Zorn J, Hogerwerf L, Velders GJM, Portengen L, Gerlofs-Nijland M, Dijkema M, Strak M, Jacobs J, Wesseling J, de Vries WJ, Mijnen-Visser S, Smit LAM, Vermeulen R, Mughini-Gras L. Simões M, et al. Among authors: wesseling j. Int J Hyg Environ Health. 2024 Jun;259:114382. doi: 10.1016/j.ijheh.2024.114382. Epub 2024 Apr 22. Int J Hyg Environ Health. 2024. PMID: 38652943 Free article.
MRI-guided optimisation of neoadjuvant chemotherapy duration in stage II-III HER2-positive breast cancer (TRAIN-3): a multicentre, single-arm, phase 2 study.
van der Voort A, Louis FM, van Ramshorst MS, Kessels R, Mandjes IA, Kemper I, Agterof MJ, van der Steeg WA, Heijns JB, van Bekkum ML, Siemerink EJ, Kuijer PM, Scholten A, Wesseling J, Vrancken Peeters MTFD, Mann RM, Sonke GS; Dutch Breast Cancer Research Group. van der Voort A, et al. Among authors: wesseling j. Lancet Oncol. 2024 May;25(5):603-613. doi: 10.1016/S1470-2045(24)00104-9. Epub 2024 Apr 5. Lancet Oncol. 2024. PMID: 38588682 Clinical Trial.
Application of deep learning on mammographies to discriminate between low and high-risk DCIS for patient participation in active surveillance trials.
Alaeikhanehshir S, Voets MM, van Duijnhoven FH, Lips EH, Groen EJ, van Oirsouw MCJ, Hwang SE, Lo JY, Wesseling J, Mann RM, Teuwen J; Grand Challenge PRECISION Consortium Steering Group. Alaeikhanehshir S, et al. Among authors: wesseling j. Cancer Imaging. 2024 Apr 5;24(1):48. doi: 10.1186/s40644-024-00691-x. Cancer Imaging. 2024. PMID: 38576031 Free PMC article.
374 results