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Treponema pallidum periplasmic and membrane proteins are recognized by circulating and skin CD4+ T cells.
Reid TB, Godornes C, Campbell VL, Laing KJ, Tantalo LC, Gomez A, Pholsena TN, Lieberman NAP, Krause TM, Cegielski VI, Culver LA, Nguyen N, Tong DQ, Hawley KL, Greninger AL, Giacani L, Cameron CE, Dombrowski JC, Wald A, Koelle DM. Reid TB, et al. Among authors: hawley kl. bioRxiv [Preprint]. 2024 Feb 29:2024.02.27.581790. doi: 10.1101/2024.02.27.581790. bioRxiv. 2024. PMID: 38464313 Free PMC article. Preprint.
Early syphilis in Guangzhou, China: presentation, molecular detection of Treponema pallidum , and genomic sequences in clinical specimens and isolates obtained by rabbit infectivity testing.
Yang L, Zhang X, Chen W, Seña AC, Zheng H, Jiang Y, Zhao P, Chen R, Wang L, Ke W, Salazar JC, Parr JB, Tucker JD, Hawley KL, Caimano MJ, Hennelly CM, Aghakanian F, Zhang F, Chen JS, Moody MA, Radolf JD, Yang B. Yang L, et al. Among authors: hawley kl. medRxiv [Preprint]. 2023 Oct 19:2023.10.17.23297169. doi: 10.1101/2023.10.17.23297169. medRxiv. 2023. PMID: 37905017 Free PMC article. Preprint.
Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326).
Ferguson MR, Delgado KN, McBride S, Orbe IC, La Vake CJ, Caimano MJ, Mendez Q, Moraes TF, Schryvers AB, Moody MA, Radolf JD, Weiner MP, Hawley KL. Ferguson MR, et al. Among authors: hawley kl. Front Immunol. 2023 Aug 22;14:1222267. doi: 10.3389/fimmu.2023.1222267. eCollection 2023. Front Immunol. 2023. PMID: 37675118 Free PMC article.
Clinical and genomic diversity of Treponema pallidum subsp. pallidum: A global, multi-center study of early syphilis to inform vaccine research.
Seña AC, Matoga MM, Yang L, Lopez-Medina E, Aghakanian F, Chen JS, Bettin EB, Caimano MJ, Chen W, Garcia-Luna JA, Hennelly CM, Jiang Y, Juliano JJ, Pospíšilová P, Ramirez L, Šmajs D, Tucker JD, Cely FV, Zheng H, Hoffman IF, Yang B, Moody MA, Hawley KL, Salazar JC, Radolf JD, Parr JB. Seña AC, et al. Among authors: hawley kl. medRxiv [Preprint]. 2023 Jul 24:2023.07.19.23291250. doi: 10.1101/2023.07.19.23291250. medRxiv. 2023. PMID: 37546832 Free PMC article. Preprint.
High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny.
Lieberman NAP, Armstrong TD, Chung B, Pfalmer D, Hennelly CM, Haynes A, Romeis E, Wang QQ, Zhang RL, Kou CX, Ciccarese G, Conte ID, Cusini M, Drago F, Nakayama SI, Lee K, Ohnishi M, Konda KA, Vargas SK, Eguiluz M, Caceres CF, Klausner JD, Mitja O, Rompalo A, Mulcahy F, Hook EW 3rd, Hoffman IF, Matoga MM, Zheng H, Yang B, Lopez-Medina E, Ramirez LG, Radolf JD, Hawley KL, Salazar JC, Lukehart SA, Seña AC, Parr JB, Giacani L, Greninger AL. Lieberman NAP, et al. Among authors: hawley kl. Front Microbiol. 2022 Sep 20;13:1007056. doi: 10.3389/fmicb.2022.1007056. eCollection 2022. Front Microbiol. 2022. PMID: 36204625 Free PMC article.
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