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Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria.
Watson FN, Shears MJ, Kalata AC, Duncombe CJ, Seilie AM, Chavtur C, Conrad E, Cruz Talavera I, Raappana A, Sather DN, Chakravarty S, Sim BKL, Hoffman SL, Tsuji M, Murphy SC. Watson FN, et al. Among authors: raappana a. Sci Rep. 2024 Feb 4;14(1):2881. doi: 10.1038/s41598-024-53118-9. Sci Rep. 2024. PMID: 38311678 Free PMC article.
Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria.
Watson FN, Shears MJ, Kalata AC, Duncombe CJ, Seilie AM, Chavtur C, Conrad E, Talavera IC, Raappana A, Sather DN, Chakravarty S, Sim BKL, Hoffman SL, Tsuji M, Murphy SC. Watson FN, et al. Among authors: raappana a. Res Sq [Preprint]. 2023 Aug 11:rs.3.rs-3243319. doi: 10.21203/rs.3.rs-3243319/v1. Res Sq. 2023. PMID: 37609210 Free PMC article. Updated. Preprint.
Coimmunization with Preerythrocytic Antigens alongside Circumsporozoite Protein Can Enhance Sterile Protection against Plasmodium Sporozoite Infection.
Vigdorovich V, Patel H, Watson A, Raappana A, Reynolds L, Selman W, Beeman S, Edlefsen PT, Kappe SHI, Sather DN. Vigdorovich V, et al. Among authors: raappana a. Microbiol Spectr. 2023 Feb 27;11(2):e0379122. doi: 10.1128/spectrum.03791-22. Online ahead of print. Microbiol Spectr. 2023. PMID: 36847573 Free PMC article.
Persistent Nonviral Plasmid Vector in Nasal Tissues Causes False-Positive SARS-CoV-2 Diagnostic Nucleic Acid Tests.
Beck IA, Styrchak S, Miller L, Mast F, Vigdorovich V, Yeung W, Ko D, Oldroyd A, Hardy S, Li S, Houck J, Jiang Y, Dambrauskas N, Darcey C, Raappana A, Selman W, Sather DN, Aitchison JD, Harrington WE, Frenkel LM. Beck IA, et al. Among authors: raappana a. Microbiol Spectr. 2022 Dec 21;10(6):e0169522. doi: 10.1128/spectrum.01695-22. Epub 2022 Oct 13. Microbiol Spectr. 2022. PMID: 36226962 Free PMC article.
Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection.
Visweswaran GRR, Vijayan K, Chandrasekaran R, Trakhimets O, Brown SL, Vigdorovich V, Yang A, Raappana A, Watson A, Selman W, Zuck M, Dambrauskas N, Kaushansky A, Sather DN. Visweswaran GRR, et al. Among authors: raappana a. PLoS Pathog. 2022 Jul 6;18(7):e1010671. doi: 10.1371/journal.ppat.1010671. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35793394 Free PMC article.
Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-CSP monoclonal antibodies.
Wilder BK, Vigdorovich V, Carbonetti S, Minkah N, Hertoghs N, Raappana A, Cardamone H, Oliver BG, Trakhimets O, Kumar S, Dambrauskas N, Arredondo SA, Camargo N, Seilie AM, Murphy SC, Kappe SHI, Sather DN. Wilder BK, et al. Among authors: raappana a. NPJ Vaccines. 2022 May 26;7(1):58. doi: 10.1038/s41541-022-00480-2. NPJ Vaccines. 2022. PMID: 35618791 Free PMC article.
Angiotensin II receptor I auto-antibodies following SARS-CoV-2 infection.
Jiang Y, Duffy F, Hadlock J, Raappana A, Styrchak S, Beck I, Mast FD, Miller LR, Chour W, Houck J, Armistead B, Duvvuri VR, Yeung W, Haglund M, Wallner J, Wallick JA, Hardy S, Oldroyd A, Ko D, Gervassi A, Murray KM, Kaplan H, Aitchison JD, Heath JR, Sather DN, Goldman JD, Frenkel L, Harrington WE. Jiang Y, et al. Among authors: raappana a. PLoS One. 2021 Nov 17;16(11):e0259902. doi: 10.1371/journal.pone.0259902. eCollection 2021. PLoS One. 2021. PMID: 34788328 Free PMC article.
Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium yoelii liver stage.
Vijayan K, Visweswaran GRR, Chandrasekaran R, Trakhimets O, Brown SL, Watson A, Zuck M, Dambrauskas N, Raappana A, Carbonetti S, Kelnhofer-Millevolte L, Glennon EKK, Postiglione R, Sather DN, Kaushansky A. Vijayan K, et al. Among authors: raappana a. Cell Rep. 2021 Aug 3;36(5):109489. doi: 10.1016/j.celrep.2021.109489. Cell Rep. 2021. PMID: 34348141 Free article.
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