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Aging impairs the neurovascular interface in the heart.
Wagner JUG, Tombor LS, Malacarne PF, Kettenhausen LM, Panthel J, Kujundzic H, Manickam N, Schmitz K, Cipca M, Stilz KA, Fischer A, Muhly-Reinholz M, Abplanalp WT, John D, Mohanta SK, Weber C, Habenicht AJR, Buchmann GK, Angendohr S, Amin E, Scherschel K, Klöcker N, Kelm M, Schüttler D, Clauss S, Günther S, Boettger T, Braun T, Bär C, Pham MD, Krishnan J, Hille S, Müller OJ, Bozoglu T, Kupatt C, Nardini E, Osmanagic-Myers S, Meyer C, Zeiher AM, Brandes RP, Luxán G, Dimmeler S. Wagner JUG, et al. Among authors: scherschel k. Science. 2023 Aug 25;381(6660):897-906. doi: 10.1126/science.ade4961. Epub 2023 Aug 24. Science. 2023. PMID: 37616346
Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias.
Jungen C, Scherschel K, Eickholt C, Kuklik P, Klatt N, Bork N, Salzbrunn T, Alken F, Angendohr S, Klene C, Mester J, Klöcker N, Veldkamp MW, Schumacher U, Willems S, Nikolaev VO, Meyer C. Jungen C, et al. Among authors: scherschel k. Nat Commun. 2017 Jan 27;8:14155. doi: 10.1038/ncomms14155. Nat Commun. 2017. PMID: 28128201 Free PMC article.
Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation.
Scherschel K, Hedenus K, Jungen C, Lemoine MD, Rübsamen N, Veldkamp MW, Klatt N, Lindner D, Westermann D, Casini S, Kuklik P, Eickholt C, Klöcker N, Shivkumar K, Christ T, Zeller T, Willems S, Meyer C. Scherschel K, et al. Sci Transl Med. 2019 May 22;11(493):eaav7770. doi: 10.1126/scitranslmed.aav7770. Sci Transl Med. 2019. PMID: 31118294 Clinical Trial.
Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation.
Jungen C, Scherschel K, Flenner F, Jee H, Rajendran P, De Jong KA, Nikolaev V, Meyer C, Ardell JL, Tompkins JD. Jungen C, et al. Among authors: scherschel k. Am J Physiol Heart Circ Physiol. 2019 Dec 1;317(6):H1328-H1341. doi: 10.1152/ajpheart.00249.2019. Epub 2019 Oct 18. Am J Physiol Heart Circ Physiol. 2019. PMID: 31625779 Free PMC article.
38 results