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A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicity.
Gall L, Jardi F, Lammens L, Piñero J, Souza TM, Rodrigues D, Jennen DGJ, de Kok TM, Coyle L, Chung SW, Ferreira S, Jo H, Beattie KA, Kelly C, Duckworth CA, Pritchard DM, Pin C. Gall L, et al. Among authors: coyle l. CPT Pharmacometrics Syst Pharmacol. 2023 Oct;12(10):1511-1528. doi: 10.1002/psp4.13029. Epub 2023 Sep 11. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37621010 Free PMC article.
Nonclinical pharmacokinetics and biodistribution of VSV-GP using methods to decouple input drug disposition and viral replication.
Dambra R, Matter A, Graca K, Akhand SS, Mehta S, Bell-Cohn A, Swenson JM, Abid S, Xin D, Lewis C, Coyle L, Wang M, Bunosso K, Maugiri M, Ruiz R, Cirillo CM, Fogal B, Grimaldi C, Vigil A, Wood C, Ashour J. Dambra R, et al. Among authors: coyle l. Mol Ther Methods Clin Dev. 2022 Dec 28;28:190-207. doi: 10.1016/j.omtm.2022.12.013. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2022. PMID: 36700123 Free PMC article.
Diuretics use in the management of bronchopulmonary dysplasia in preterm infants: A systematic review.
Ó Briain E, Byrne AO, Dowling J, Kiernan J, Lynch JCR, Alomairi L, Coyle L, Mulkerrin L, Mockler D, Fitzgerald G, Rehman LU, Semova G, Isweisi E, O'Sullivan A, O'Connor P, Mulligan K, Branagan A, Roche E, Meehan J, Molloy E. Ó Briain E, et al. Among authors: coyle l. Acta Paediatr. 2024 Mar;113(3):394-402. doi: 10.1111/apa.17093. Epub 2024 Jan 12. Acta Paediatr. 2024. PMID: 38214373 Review.
Deep learning uncertainty quantification for clinical text classification.
Peluso A, Danciu I, Yoon HJ, Yusof JM, Bhattacharya T, Spannaus A, Schaefferkoetter N, Durbin EB, Wu XC, Stroup A, Doherty J, Schwartz S, Wiggins C, Coyle L, Penberthy L, Tourassi GD, Gao S. Peluso A, et al. Among authors: coyle l. J Biomed Inform. 2024 Jan;149:104576. doi: 10.1016/j.jbi.2023.104576. Epub 2023 Dec 13. J Biomed Inform. 2024. PMID: 38101690 Free article.
118 results