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A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicity.
Gall L, Jardi F, Lammens L, Piñero J, Souza TM, Rodrigues D, Jennen DGJ, de Kok TM, Coyle L, Chung SW, Ferreira S, Jo H, Beattie KA, Kelly C, Duckworth CA, Pritchard DM, Pin C. Gall L, et al. Among authors: duckworth ca. CPT Pharmacometrics Syst Pharmacol. 2023 Oct;12(10):1511-1528. doi: 10.1002/psp4.13029. Epub 2023 Sep 11. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37621010 Free PMC article.
Gastrin increases murine intestinal crypt regeneration following injury.
Ottewell PD, Duckworth CA, Varro A, Dimaline R, Wang TC, Watson AJ, Dockray GJ, Pritchard DM. Ottewell PD, et al. Among authors: duckworth ca. Gastroenterology. 2006 Apr;130(4):1169-80. doi: 10.1053/j.gastro.2005.12.033. Gastroenterology. 2006. PMID: 16618411
62 results