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Tumor immunogenicity dictates reliance on TCF1 in CD8+ T cells for response to immunotherapy.
Escobar G, Tooley K, Oliveras JP, Huang L, Cheng H, Bookstaver ML, Edwards C, Froimchuk E, Xue C, Mangani D, Krishnan RK, Hazel N, Rutigliani C, Jewell CM, Biasco L, Anderson AC. Escobar G, et al. Among authors: anderson ac. Cancer Cell. 2023 Sep 11;41(9):1662-1679.e7. doi: 10.1016/j.ccell.2023.08.001. Epub 2023 Aug 24. Cancer Cell. 2023. PMID: 37625402
Tim-3 finds its place in the cancer immunotherapy landscape.
Acharya N, Sabatos-Peyton C, Anderson AC. Acharya N, et al. Among authors: anderson ac. J Immunother Cancer. 2020 Jun;8(1):e000911. doi: 10.1136/jitc-2020-000911. J Immunother Cancer. 2020. PMID: 32601081 Free PMC article. Review.
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment.
Acharya N, Madi A, Zhang H, Klapholz M, Escobar G, Dulberg S, Christian E, Ferreira M, Dixon KO, Fell G, Tooley K, Mangani D, Xia J, Singer M, Bosenberg M, Neuberg D, Rozenblatt-Rosen O, Regev A, Kuchroo VK, Anderson AC. Acharya N, et al. Among authors: anderson ac. Immunity. 2020 Sep 15;53(3):658-671.e6. doi: 10.1016/j.immuni.2020.08.005. Immunity. 2020. PMID: 32937153 Free PMC article.
PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis.
Moreira TG, Mangani D, Cox LM, Leibowitz J, Lobo ELC, Oliveira MA, Gauthier CD, Nakagaki BN, Willocq V, Song A, Guo L, Lima DCA, Murugaiyan G, Butovsky O, Gabriely G, Anderson AC, Rezende RM, Faria AMC, Weiner HL. Moreira TG, et al. Among authors: anderson ac. Nat Commun. 2021 Aug 13;12(1):4907. doi: 10.1038/s41467-021-25115-3. Nat Commun. 2021. PMID: 34389726 Free PMC article.
Spatial determinants of CD8+ T cell differentiation in cancer.
Tooley KA, Escobar G, Anderson AC. Tooley KA, et al. Among authors: anderson ac. Trends Cancer. 2022 Aug;8(8):642-654. doi: 10.1016/j.trecan.2022.04.003. Epub 2022 May 5. Trends Cancer. 2022. PMID: 35527216 Free PMC article. Review.
Learning from the nexus of autoimmunity and cancer.
Mangani D, Yang D, Anderson AC. Mangani D, et al. Among authors: anderson ac. Immunity. 2023 Feb 14;56(2):256-271. doi: 10.1016/j.immuni.2023.01.022. Immunity. 2023. PMID: 36792572 Free PMC article. Review.
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling.
Cadinu P, Sivanathan KN, Misra A, Xu RJ, Mangani D, Yang E, Rone JM, Tooley K, Kye YC, Bod L, Geistlinger L, Lee T, Ono N, Wang G, Sanmarco L, Quintana FJ, Anderson AC, Kuchroo VK, Moffitt JR, Nowarski R. Cadinu P, et al. Among authors: anderson ac. bioRxiv [Preprint]. 2023 May 9:2023.05.08.539701. doi: 10.1101/2023.05.08.539701. bioRxiv. 2023. PMID: 37214800 Free PMC article. Updated. Preprint.
TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.
Ausejo-Mauleon I, Labiano S, de la Nava D, Laspidea V, Zalacain M, Marrodán L, García-Moure M, González-Huarriz M, Hervás-Corpión I, Dhandapani L, Vicent S, Collantes M, Peñuelas I, Becher OJ, Filbin MG, Jiang L, Labelle J, de Biagi-Junior CAO, Nazarian J, Laternser S, Phoenix TN, van der Lugt J, Kranendonk M, Hoogendijk R, Mueller S, De Andrea C, Anderson AC, Guruceaga E, Koschmann C, Yadav VN, Gállego Pérez-Larraya J, Patiño-García A, Pastor F, Alonso MM. Ausejo-Mauleon I, et al. Among authors: anderson ac. Cancer Cell. 2023 Nov 13;41(11):1911-1926.e8. doi: 10.1016/j.ccell.2023.09.001. Epub 2023 Oct 5. Cancer Cell. 2023. PMID: 37802053 Free PMC article.
357 results