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Del1 Is a Growth Factor for Skeletal Progenitor Cells in the Fracture Callus.
Sun Y, Boyko T, Marecic O, Struck D, Mann RK, Andrew TW, Lopez M, Tong X, Goodman SB, Yang F, Longaker MT, Chan CKF, Yang GP. Sun Y, et al. Among authors: marecic o. Biomolecules. 2023 Aug 3;13(8):1214. doi: 10.3390/biom13081214. Biomolecules. 2023. PMID: 37627279 Free PMC article.
Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration.
Andrew TW, Koepke LS, Wang Y, Lopez M, Steininger H, Struck D, Boyko T, Ambrosi TH, Tong X, Sun Y, Gulati GS, Murphy MP, Marecic O, Telvin R, Schallmoser K, Strunk D, Seita J, Goodman SB, Yang F, Longaker MT, Yang GP, Chan CKF. Andrew TW, et al. Among authors: marecic o. Nat Commun. 2022 Oct 30;13(1):6491. doi: 10.1038/s41467-022-34063-5. Nat Commun. 2022. PMID: 36310174 Free PMC article.
Aged skeletal stem cells generate an inflammatory degenerative niche.
Ambrosi TH, Marecic O, McArdle A, Sinha R, Gulati GS, Tong X, Wang Y, Steininger HM, Hoover MY, Koepke LS, Murphy MP, Sokol J, Seo EY, Tevlin R, Lopez M, Brewer RE, Mascharak S, Lu L, Ajanaku O, Conley SD, Seita J, Morri M, Neff NF, Sahoo D, Yang F, Weissman IL, Longaker MT, Chan CKF. Ambrosi TH, et al. Among authors: marecic o. Nature. 2021 Sep;597(7875):256-262. doi: 10.1038/s41586-021-03795-7. Epub 2021 Aug 11. Nature. 2021. PMID: 34381212 Free PMC article.
Articular cartilage regeneration by activated skeletal stem cells.
Murphy MP, Koepke LS, Lopez MT, Tong X, Ambrosi TH, Gulati GS, Marecic O, Wang Y, Ransom RC, Hoover MY, Steininger H, Zhao L, Walkiewicz MP, Quarto N, Levi B, Wan DC, Weissman IL, Goodman SB, Yang F, Longaker MT, Chan CKF. Murphy MP, et al. Among authors: marecic o. Nat Med. 2020 Oct;26(10):1583-1592. doi: 10.1038/s41591-020-1013-2. Epub 2020 Aug 17. Nat Med. 2020. PMID: 32807933 Free PMC article.
Geriatric fragility fractures are associated with a human skeletal stem cell defect.
Ambrosi TH, Goodnough LH, Steininger HM, Hoover MY, Kim E, Koepke LS, Marecic O, Zhao L, Seita J, Bishop JA, Gardner MJ, Chan CKF. Ambrosi TH, et al. Among authors: marecic o. Aging Cell. 2020 Jul;19(7):e13164. doi: 10.1111/acel.13164. Epub 2020 Jun 14. Aging Cell. 2020. PMID: 32537886 Free PMC article.
Mechanoresponsive stem cells acquire neural crest fate in jaw regeneration.
Ransom RC, Carter AC, Salhotra A, Leavitt T, Marecic O, Murphy MP, Lopez ML, Wei Y, Marshall CD, Shen EZ, Jones RE, Sharir A, Klein OD, Chan CKF, Wan DC, Chang HY, Longaker MT. Ransom RC, et al. Among authors: marecic o. Nature. 2018 Nov;563(7732):514-521. doi: 10.1038/s41586-018-0650-9. Epub 2018 Oct 24. Nature. 2018. PMID: 30356216 Free PMC article.
Identification of the Human Skeletal Stem Cell.
Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, Leavitt T, Lu WJ, Nguyen A, Conley SD, Salhotra A, Ambrosi TH, Borrelli MR, Siebel T, Chan K, Schallmoser K, Seita J, Sahoo D, Goodnough H, Bishop J, Gardner M, Majeti R, Wan DC, Goodman S, Weissman IL, Chang HY, Longaker MT. Chan CKF, et al. Among authors: marecic o. Cell. 2018 Sep 20;175(1):43-56.e21. doi: 10.1016/j.cell.2018.07.029. Cell. 2018. PMID: 30241615 Free PMC article.
Isolation and functional assessment of mouse skeletal stem cell lineage.
Gulati GS, Murphy MP, Marecic O, Lopez M, Brewer RE, Koepke LS, Manjunath A, Ransom RC, Salhotra A, Weissman IL, Longaker MT, Chan CKF. Gulati GS, et al. Among authors: marecic o. Nat Protoc. 2018 Jun;13(6):1294-1309. doi: 10.1038/nprot.2018.041. Epub 2018 May 10. Nat Protoc. 2018. PMID: 29748647 Free PMC article.
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.
Janda CY, Dang LT, You C, Chang J, de Lau W, Zhong ZA, Yan KS, Marecic O, Siepe D, Li X, Moody JD, Williams BO, Clevers H, Piehler J, Baker D, Kuo CJ, Garcia KC. Janda CY, et al. Among authors: marecic o. Nature. 2017 May 11;545(7653):234-237. doi: 10.1038/nature22306. Epub 2017 May 3. Nature. 2017. PMID: 28467818 Free PMC article.
Pharmacological rescue of diabetic skeletal stem cell niches.
Tevlin R, Seo EY, Marecic O, McArdle A, Tong X, Zimdahl B, Malkovskiy A, Sinha R, Gulati G, Li X, Wearda T, Morganti R, Lopez M, Ransom RC, Duldulao CR, Rodrigues M, Nguyen A, Januszyk M, Maan Z, Paik K, Yapa KS, Rajadas J, Wan DC, Gurtner GC, Snyder M, Beachy PA, Yang F, Goodman SB, Weissman IL, Chan CK, Longaker MT. Tevlin R, et al. Among authors: marecic o. Sci Transl Med. 2017 Jan 11;9(372):eaag2809. doi: 10.1126/scitranslmed.aag2809. Sci Transl Med. 2017. PMID: 28077677 Free PMC article.
18 results