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Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson's Disease as a Multi-System Process.
Videlock EJ, Hatami A, Zhu C, Kawaguchi R, Chen H, Khan T, Yehya AHS, Stiles L, Joshi S, Hoffman JM, Law KM, Rankin CR, Chang L, Maidment NT, John V, Geschwind DH, Pothoulakis C. Videlock EJ, et al. Among authors: geschwind dh. J Parkinsons Dis. 2023;13(7):1127-1147. doi: 10.3233/JPD-223568. J Parkinsons Dis. 2023. PMID: 37638450 Free PMC article.
2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer's resilience.
Kumar A, Karuppagounder SS, Chen Y, Corona C, Kawaguchi R, Cheng Y, Balkaya M, Sagdullaev BT, Wen Z, Stuart C, Cho S, Ming GL, Tuvikene J, Timmusk T, Geschwind DH, Ratan RR. Kumar A, et al. Among authors: geschwind dh. Neuron. 2023 Sep 20;111(18):2831-2846.e10. doi: 10.1016/j.neuron.2023.06.013. Epub 2023 Jul 14. Neuron. 2023. PMID: 37453419
Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells.
Tian F, Cheng Y, Zhou S, Wang Q, Monavarfeshani A, Gao K, Jiang W, Kawaguchi R, Wang Q, Tang M, Donahue R, Meng H, Zhang Y, Jacobi A, Yan W, Yin J, Cai X, Yang Z, Hegarty S, Stanicka J, Dmitriev P, Taub D, Zhu J, Woolf CJ, Sanes JR, Geschwind DH, He Z. Tian F, et al. Among authors: geschwind dh. Neuron. 2023 Feb 1;111(3):444. doi: 10.1016/j.neuron.2023.01.008. Neuron. 2023. PMID: 36731430 Free PMC article. No abstract available.
Sarm1 is not necessary for activation of neuron-intrinsic growth programs yet required for the Schwann cell repair response and peripheral nerve regeneration.
Schmitd LB, Hafner H, Ward A, Asghari Adib E, Biscola NP, Kohen R, Patel M, Williamson RE, Desai E, Bennett J, Saxman G, Athaiya M, Wilborn D, Shumpert J, Zhao XF, Kawaguchi R, Geschwind DH, Hoke A, Shrager P, Collins CA, Havton LA, Kalinski AL, Giger RJ. Schmitd LB, et al. Among authors: geschwind dh. bioRxiv [Preprint]. 2024 Apr 17:2024.03.04.583374. doi: 10.1101/2024.03.04.583374. bioRxiv. 2024. PMID: 38496662 Free PMC article. Preprint.
Brain-wide neuronal circuit connectome of human glioblastoma.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Dong W, Zhang F, Park KH, Galanaugh J, Sambangi A, Yang Q, Kim SH, Wheeler G, Goncalves T, Wang Q, Geschwind D, Kawaguchi R, Wang H, Xu F, Binder ZA, Chen IH, Pai EL, Stone S, Nasrallah M, Christian KM, Fuccillo M, O'Rourke DM, Ma M, Ming GL, Song H. Sun Y, et al. bioRxiv [Preprint]. 2024 Mar 4:2024.03.01.583047. doi: 10.1101/2024.03.01.583047. bioRxiv. 2024. PMID: 38496540 Free PMC article. Preprint.
587 results