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Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson's Disease as a Multi-System Process.
Videlock EJ, Hatami A, Zhu C, Kawaguchi R, Chen H, Khan T, Yehya AHS, Stiles L, Joshi S, Hoffman JM, Law KM, Rankin CR, Chang L, Maidment NT, John V, Geschwind DH, Pothoulakis C. Videlock EJ, et al. Among authors: pothoulakis c. J Parkinsons Dis. 2023;13(7):1127-1147. doi: 10.3233/JPD-223568. J Parkinsons Dis. 2023. PMID: 37638450 Free PMC article.
Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain.
Latorre R, Hegron A, Peach CJ, Teng S, Tonello R, Retamal JS, Klein-Cloud R, Bok D, Jensen DD, Gottesman-Katz L, Rientjes J, Veldhuis NA, Poole DP, Schmidt BL, Pothoulakis CH, Rankin C, Xie Y, Koon HW, Bunnett NW. Latorre R, et al. Among authors: pothoulakis ch. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2112059119. doi: 10.1073/pnas.2112059119. Proc Natl Acad Sci U S A. 2022. PMID: 35110404 Free PMC article.
The Colonic Mucosal MicroRNAs, MicroRNA-219a-5p, and MicroRNA-338-3p Are Downregulated in Irritable Bowel Syndrome and Are Associated With Barrier Function and MAPK Signaling.
Mahurkar-Joshi S, Rankin CR, Videlock EJ, Soroosh A, Verma A, Khandadash A, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Mahurkar-Joshi S, et al. Among authors: pothoulakis c. Gastroenterology. 2021 Jun;160(7):2409-2422.e19. doi: 10.1053/j.gastro.2021.02.040. Epub 2021 Feb 20. Gastroenterology. 2021. PMID: 33617890 Free PMC article.
Blockage of protease-activated receptor 2 exacerbates inflammation in high-fat environment partly through autophagy inhibition.
Her JY, Lee Y, Kim SJ, Heo G, Choo J, Kim Y, Howe C, Rhee SH, Yu HS, Chung HY, Pothoulakis C, Im E. Her JY, et al. Among authors: pothoulakis c. Am J Physiol Gastrointest Liver Physiol. 2021 Jan 1;320(1):G30-G42. doi: 10.1152/ajpgi.00203.2020. Epub 2020 Nov 4. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33146548 Free article.
Role and mechanisms of exosomal miRNAs in IBD pathophysiology.
Wani S, Man Law IK, Pothoulakis C. Wani S, et al. Among authors: pothoulakis c. Am J Physiol Gastrointest Liver Physiol. 2020 Dec 1;319(6):G646-G654. doi: 10.1152/ajpgi.00295.2020. Epub 2020 Oct 7. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 33026230 Free PMC article. Review.
261 results