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Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes.
Le Guen Y, Luo G, Ambati A, Damotte V, Jansen I, Yu E, Nicolas A, de Rojas I, Peixoto Leal T, Miyashita A, Bellenguez C, Lian MM, Parveen K, Morizono T, Park H, Grenier-Boley B, Naito T, Küçükali F, Talyansky SD, Yogeshwar SM, Sempere V, Satake W, Alvarez V, Arosio B, Belloy ME, Benussi L, Boland A, Borroni B, Bullido MJ, Caffarra P, Clarimon J, Daniele A, Darling D, Debette S, Deleuze JF, Dichgans M, Dufouil C, During E, Düzel E, Galimberti D, Garcia-Ribas G, García-Alberca JM, García-González P, Giedraitis V, Goldhardt O, Graff C, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Holstege H, Hort J, Jung YJ, Jürgen D, Kern S, Kuulasmaa T, Lee KH, Lin L, Masullo C, Mecocci P, Mehrabian S, de Mendonça A, Boada M, Mir P, Moebus S, Moreno F, Nacmias B, Nicolas G, Niida S, Nordestgaard BG, Papenberg G, Papma J, Parnetti L, Pasquier F, Pastor P, Peters O, Pijnenburg YAL, Piñol-Ripoll G, Popp J, Porcel LM, Puerta R, Pérez-Tur J, Rainero I, Ramakers I, Real LM, Riedel-Heller S, Rodriguez-Rodriguez E, Ross OA, Royo LJ, Rujescu D, Scarmeas N, Scheltens P, Scherbaum N, Schneider A, Seripa D, Skoog I, Solfrizzi V, Spalletta G, Squassina A, van Swieten J, Sánchez-Valle R, Tan EK, Tegos T… See abstract for full author list ➔ Le Guen Y, et al. Among authors: wiltfang j. Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2302720120. doi: 10.1073/pnas.2302720120. Epub 2023 Aug 29. Proc Natl Acad Sci U S A. 2023. PMID: 37643212 Free PMC article.
Association of SORL1 gene variants with Alzheimer's disease.
Kölsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Teipel SJ, Kornhuber J, Frölich L, Heuser I, Peters O, Wiese B, Kaduszkiewicz H, van den Bussche H, Hüll M, Kurz A, Rüther E, Henn FA, Maier W. Kölsch H, et al. Among authors: wiltfang j. Brain Res. 2009 Apr 6;1264:1-6. doi: 10.1016/j.brainres.2009.01.044. Epub 2009 Feb 3. Brain Res. 2009. PMID: 19368828
Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form.
Klafki HW, Lewczuk P, Kamrowski-Kruck H, Maler JM, Müller K, Peters O, Heuser I, Jessen F, Popp J, Frölich L, Wolf S, Prinz B, Luckhaus C, Schröder J, Pantel J, Gertz HJ, Kölsch H, Müller BW, Esselmann H, Bibl M, Kornhuber J, Wiltfang J. Klafki HW, et al. Among authors: wiltfang j. J Alzheimers Dis. 2009;18(3):613-22. doi: 10.3233/JAD-2009-1167. J Alzheimers Dis. 2009. PMID: 19625747
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J. Harold D, et al. Among authors: wiltfang j. Nat Genet. 2009 Oct;41(10):1088-93. doi: 10.1038/ng.440. Epub 2009 Sep 6. Nat Genet. 2009. PMID: 19734902 Free PMC article.
Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease.
Teipel SJ, Ewers M, Wolf S, Jessen F, Kölsch H, Arlt S, Luckhaus C, Schönknecht P, Schmidtke K, Heuser I, Frölich L, Ende G, Pantel J, Wiltfang J, Rakebrandt F, Peters O, Born C, Kornhuber J, Hampel H. Teipel SJ, et al. Among authors: wiltfang j. Psychiatry Res. 2010 Jun 30;182(3):244-50. doi: 10.1016/j.pscychresns.2010.03.003. Epub 2010 May 20. Psychiatry Res. 2010. PMID: 20493672
cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases.
Spitzer P, Klafki HW, Blennow K, Buée L, Esselmann H, Herruka SK, Jimenez C, Klivenyi P, Lewczuk P, Maler JM, Markus K, Meyer HE, Morris C, Müller T, Otto M, Parnetti L, Soininen H, Schraen S, Teunissen C, Vecsei L, Zetterberg H, Wiltfang J. Spitzer P, et al. Among authors: wiltfang j. Int J Alzheimers Dis. 2010 Sep 19;2010:548145. doi: 10.4061/2010/548145. Int J Alzheimers Dis. 2010. PMID: 20886057 Free PMC article.
998 results