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Maternal age and gonadotrophin elevation cooperatively decrease viable ovulated oocytes and increase ootoxicity, chromosome-, and spindle-misalignments: '2-Hit' and 'FSH-OoToxicity' mechanisms as new reproductive aging hypotheses.
Bernstein LR, Mackenzie ACL, Durkin K, Kraemer DC, Chaffin CL, Merchenthaler I. Bernstein LR, et al. Among authors: kraemer dc. Mol Hum Reprod. 2023 Sep 30;29(10):gaad030. doi: 10.1093/molehr/gaad030. Mol Hum Reprod. 2023. PMID: 37643633
Complex multi-enhancer contacts captured by genome architecture mapping.
Beagrie RA, Scialdone A, Schueler M, Kraemer DC, Chotalia M, Xie SQ, Barbieri M, de Santiago I, Lavitas LM, Branco MR, Fraser J, Dostie J, Game L, Dillon N, Edwards PA, Nicodemi M, Pombo A. Beagrie RA, et al. Among authors: kraemer dc. Nature. 2017 Mar 23;543(7646):519-524. doi: 10.1038/nature21411. Epub 2017 Mar 8. Nature. 2017. PMID: 28273065 Free PMC article.
Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation.
Fraser J, Ferrai C, Chiariello AM, Schueler M, Rito T, Laudanno G, Barbieri M, Moore BL, Kraemer DC, Aitken S, Xie SQ, Morris KJ, Itoh M, Kawaji H, Jaeger I, Hayashizaki Y, Carninci P, Forrest AR; FANTOM Consortium; Semple CA, Dostie J, Pombo A, Nicodemi M. Fraser J, et al. Among authors: kraemer dc. Mol Syst Biol. 2015 Dec 23;11(12):852. doi: 10.15252/msb.20156492. Mol Syst Biol. 2015. PMID: 26700852 Free PMC article.
89 results