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A loss-of-function CCR2 variant is associated with lower cardiovascular risk.
Georgakis MK, Malik R, Bounkari OE, Hasbani NR, Li J, Huffman JE, Shakt G, Tack RWP, Kimball TN, Asare Y, Morrison AC, Tsao NL, Judy R, Mitchell BD, Xu H, Montasser ME, Do R, Kenny EE, Loos RJF, Terry JG, Carr JJ, Bis JC, Psaty BM, Longstreth WT, Young KA, Lutz SM, Cho MH, Broome J, Khan AT, Wang FF, Heard-Costa N, Seshadri S, Vasan RS, Palmer ND, Freedman BI, Bowden DW, Yanek LR, Kral BG, Becker LC, Peyser PA, Bielak LF, Ammous F, Carson AP, Hall ME, Raffield LM, Rich SS, Post WS, Tracy RP, Taylor KD, Guo X, Mahaney MC, Curran JE, Blangero J, Clarke SL, Haessler JW, Hu Y, Assimes TL, Kooperberg C, Bernhagen J, Anderson CD, Damrauer SM, Zand R, Rotter JI, de Vries PS, Dichgans M. Georgakis MK, et al. Among authors: shakt g. medRxiv [Preprint]. 2024 May 6:2023.08.14.23294063. doi: 10.1101/2023.08.14.23294063. medRxiv. 2024. PMID: 37645892 Free PMC article. Preprint.
Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program.
Klarin D, Devineni P, Sendamarai AK, Angueira AR, Graham SE, Shen YH, Levin MG, Pirruccello JP, Surakka I, Karnam PR, Roychowdhury T, Li Y, Wang M, Aragam KG, Paruchuri K, Zuber V, Shakt GE, Tsao NL, Judy RL, Vy HMT, Verma SS, Rader DJ, Do R, Bavaria JE, Nadkarni GN, Ritchie MD; VA Million Veteran Program; Burgess S, Guo DC, Ellinor PT, LeMaire SA, Milewicz DM, Willer CJ, Natarajan P, Tsao PS, Pyarajan S, Damrauer SM. Klarin D, et al. Among authors: shakt ge. Nat Genet. 2023 Jul;55(7):1106-1115. doi: 10.1038/s41588-023-01420-z. Epub 2023 Jun 12. Nat Genet. 2023. PMID: 37308786 Free PMC article.
Evaluation of the Performance of the RECODe Equation with the Addition of Polygenic Risk Scores for Adverse Cardiovascular Outcomes in Individuals with Type II Diabetes.
Tsao NL, Judy R, Levin MG, Shakt G; Regeneron Genetics Center; Penn Medicine BioBank; Voight BF, Chen J, Damrauer SM. Tsao NL, et al. Among authors: shakt g. medRxiv [Preprint]. 2023 May 5:2023.05.03.23289457. doi: 10.1101/2023.05.03.23289457. medRxiv. 2023. PMID: 37205500 Free PMC article. Preprint.
Metabolite patterns associated with individual response to supervised exercise therapy in patients with intermittent claudication.
Bellomo TR, Tsao NL, Johnston-Cox H, Borkowski K, Shakt G, Judy R, Moore J, Ractcliffe SJ, Fiehn O, Floyd TF, Wehrli FW, Mohler E, Newman JW, Damrauer SM. Bellomo TR, et al. Among authors: shakt g. JVS Vasc Sci. 2022 Oct 25;3:379-388. doi: 10.1016/j.jvssci.2022.10.002. eCollection 2022. JVS Vasc Sci. 2022. PMID: 36568282 Free PMC article.