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A systems approach reveals species differences in hepatic stress response capacity.
Russomanno G, Sison-Young R, Livoti LA, Coghlan H, Jenkins RE, Kunnen SJ, Fisher CP, Reddyhoff D, Gardner I, Rehman AH, Fenwick SW, Jones AR, Vermeil De Conchard G, Simonin G, Bertheux H, Weaver RJ, Johnson RL, Liguori MJ, Clausznitzer D, Stevens JL, Goldring CE, Copple IM. Russomanno G, et al. Among authors: jenkins re. Toxicol Sci. 2023 Oct 30;196(1):112-125. doi: 10.1093/toxsci/kfad085. Toxicol Sci. 2023. PMID: 37647630 Free PMC article.
Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.
Kitteringham NR, Abdullah A, Walsh J, Randle L, Jenkins RE, Sison R, Goldring CE, Powell H, Sanderson C, Williams S, Higgins L, Yamamoto M, Hayes J, Park BK. Kitteringham NR, et al. Among authors: jenkins re. J Proteomics. 2010 Jun 16;73(8):1612-31. doi: 10.1016/j.jprot.2010.03.018. Epub 2010 Apr 24. J Proteomics. 2010. PMID: 20399915 Free PMC article.
Safety pharmacology--current and emerging concepts.
Hamdam J, Sethu S, Smith T, Alfirevic A, Alhaidari M, Atkinson J, Ayala M, Box H, Cross M, Delaunois A, Dermody A, Govindappa K, Guillon JM, Jenkins R, Kenna G, Lemmer B, Meecham K, Olayanju A, Pestel S, Rothfuss A, Sidaway J, Sison-Young R, Smith E, Stebbings R, Tingle Y, Valentin JP, Williams A, Williams D, Park K, Goldring C. Hamdam J, et al. Toxicol Appl Pharmacol. 2013 Dec 1;273(2):229-41. doi: 10.1016/j.taap.2013.04.039. Epub 2013 Jun 1. Toxicol Appl Pharmacol. 2013. PMID: 23732082 Review.
Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study.
Jones RP, Sutton P, Greensmith RM, Santoyo-Castelazo A, Carr DF, Jenkins R, Rowe C, Hamlett J, Park BK, Terlizzo M, O'Grady E, Ghaneh P, Fenwick SW, Malik HZ, Poston GJ, Kitteringham NR. Jones RP, et al. Cancer Chemother Pharmacol. 2013 Aug;72(2):359-68. doi: 10.1007/s00280-013-2199-5. Epub 2013 Jun 12. Cancer Chemother Pharmacol. 2013. PMID: 23756919 Clinical Trial.
152 results