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Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping.
Yang H, Sui P, Guo Y, Chen S, Maloof ME, Ge G, Nihozeko F, Delma CR, Zhu G, Zhang P, Ye Z, Medina EA, Ayad NG, Mesa R, Nimer SD, Chiang CM, Xu M, Chen Y, Yang FC. Yang H, et al. Among authors: ayad ng. EMBO Rep. 2023 Oct 9;24(10):e57032. doi: 10.15252/embr.202357032. Epub 2023 Aug 31. EMBO Rep. 2023. PMID: 37650863 Free article.
RAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma.
Jermakowicz AM, Kurimchak AM, Johnson KJ, Bourgain-Guglielmetti F, Kaeppeli S, Affer M, Pradhyumnan H, Suter RK, Walters W, Cepero M, Duncan JS, Ayad NG. Jermakowicz AM, et al. Among authors: ayad ng. Sci Rep. 2024 Apr 23;14(1):9284. doi: 10.1038/s41598-024-60031-8. Sci Rep. 2024. PMID: 38654040 Free PMC article.
Kinome-Wide Virtual Screening by Multi-Task Deep Learning.
Hu J, Allen BK, Stathias V, Ayad NG, Schürer SC. Hu J, et al. Among authors: ayad ng. Int J Mol Sci. 2024 Feb 22;25(5):2538. doi: 10.3390/ijms25052538. Int J Mol Sci. 2024. PMID: 38473785 Free PMC article.
A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog-Dependent Tumor Growth.
Yang F, Rodriguez-Blanco J, Long J, Swiderska-Syn M, Wynn DT, Li B, Shen C, Nayak A, Ban Y, Sun X, Suter RK, McCrea HJ, Capobianco AJ, Ayad NG, Robbins DJ. Yang F, et al. Among authors: ayad ng. Mol Cancer Res. 2022 Nov 3;20(11):1598-1610. doi: 10.1158/1541-7786.MCR-22-0182. Mol Cancer Res. 2022. PMID: 35925047 Free PMC article.
A multiparametric pharmacogenomic strategy for drug repositioning predicts therapeutic efficacy for glioblastoma cell lines.
Shah AH, Suter R, Gudoor P, Doucet-O'Hare TT, Stathias V, Cajigas I, de la Fuente M, Govindarajan V, Morell AA, Eichberg DG, Luther E, Lu VM, Heiss J, Komotar RJ, Ivan ME, Schurer S, Gilbert MR, Ayad NG. Shah AH, et al. Among authors: ayad ng. Neurooncol Adv. 2021 Dec 31;4(1):vdab192. doi: 10.1093/noajnl/vdab192. eCollection 2022 Jan-Dec. Neurooncol Adv. 2021. PMID: 35118385 Free PMC article.
51 results