Chen Y - Search Results

1

Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade.

Goswami S, Raychaudhuri D, Singh P, Natarajan SM, Chen Y, Poon C, Hennessey M, Tannir AJ, Zhang J, Anandhan S, Kerrigan BP, Macaluso MD, He Z, Jindal S, Lang FF, Basu S, Sharma P. Goswami S, et al. Among authors: chen y. Nat Cancer. 2023 Oct;4(10):1455-1473. doi: 10.1038/s43018-023-00620-0. Epub 2023 Aug 31. Nat Cancer. 2023. PMID: 37653141

2

ARID1A mutation plus CXCL13 expression act as combinatorial biomarkers to predict responses to immune checkpoint therapy in mUCC.

Goswami S, Chen Y, Anandhan S, Szabo PM, Basu S, Blando JM, Liu W, Zhang J, Natarajan SM, Xiong L, Guan B, Yadav SS, Saci A, Allison JP, Galsky MD, Sharma P. Goswami S, et al. Among authors: chen y. Sci Transl Med. 2020 Jun 17;12(548):eabc4220. doi: 10.1126/scitranslmed.abc4220. Sci Transl Med. 2020. PMID: 32554706

3

CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.

Saintigny P, Massarelli E, Lin S, Ahn YH, Chen Y, Goswami S, Erez B, O'Reilly MS, Liu D, Lee JJ, Zhang L, Ping Y, Behrens C, Solis Soto LM, Heymach JV, Kim ES, Herbst RS, Lippman SM, Wistuba II, Hong WK, Kurie JM, Koo JS. Saintigny P, et al. Among authors: chen y. Cancer Res. 2013 Jan 15;73(2):571-82. doi: 10.1158/0008-5472.CAN-12-0263. Epub 2012 Nov 30. Cancer Res. 2013. PMID: 23204236 Free PMC article.

4

Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor.

Chen Y, Deng J, Fujimoto J, Kadara H, Men T, Lotan D, Lotan R. Chen Y, et al. Cancer Res. 2010 Nov 1;70(21):8917-26. doi: 10.1158/0008-5472.CAN-10-0518. Epub 2010 Oct 19. Cancer Res. 2010. PMID: 20959490 Free PMC article.

5

Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis.

Chen Z, Zheng L, Chen Y, Liu X, Kawakami M, Mustachio LM, Roszik J, Ferry-Galow KV, Parchment RE, Liu X, Andresson T, Duncan G, Kurie JM, Rodriguez-Canales J, Liu X, Dmitrovsky E. Chen Z, et al. Among authors: chen y. Cancer Biol Ther. 2022 Dec 31;23(1):265-280. doi: 10.1080/15384047.2022.2054242. Cancer Biol Ther. 2022. PMID: 35387560 Free PMC article.

6

Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy.

Zheng L, Chen Z, Kawakami M, Chen Y, Roszik J, Mustachio LM, Kurie JM, Villalobos P, Lu W, Behrens C, Mino B, Solis LM, Silvester J, Thu KL, Cescon DW, Rodriguez-Canales J, Wistuba II, Mak TW, Liu X, Dmitrovsky E. Zheng L, et al. Among authors: chen z, chen y. Mol Cancer Ther. 2019 Oct;18(10):1775-1786. doi: 10.1158/1535-7163.MCT-18-0864. Epub 2019 Jul 29. Mol Cancer Ther. 2019. PMID: 31358662

7

Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis.

Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, Lotan R. Deng J, et al. Cancer Prev Res (Phila). 2010 Apr;3(4):424-37. doi: 10.1158/1940-6207.CAPR-10-0032. Epub 2010 Mar 30. Cancer Prev Res (Phila). 2010. PMID: 20354164 Free PMC article.

8

Author Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe²⁺-binding.

Guo HF, Tsai CL, Terajima M, Tan X, Banerjee P, Miller MD, Liu X, Yu J, Byemerwa J, Alvarado S, Kaoud TS, Dalby KN, Bota-Rabassedas N, Chen Y, Yamauchi M, Tainer JA, Phillips GN Jr, Kurie JM. Guo HF, et al. Among authors: chen y. Nat Commun. 2018 Jul 10;9(1):2719. doi: 10.1038/s41467-018-05295-1. Nat Commun. 2018. PMID: 29988035 Free PMC article.

9

Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe²⁺-binding.

Guo HF, Tsai CL, Terajima M, Tan X, Banerjee P, Miller MD, Liu X, Yu J, Byemerwa J, Alvarado S, Kaoud TS, Dalby KN, Bota-Rabassedas N, Chen Y, Yamauchi M, Tainer JA, Phillips GN Jr, Kurie JM. Guo HF, et al. Among authors: chen y. Nat Commun. 2018 Feb 6;9(1):512. doi: 10.1038/s41467-018-02859-z. Nat Commun. 2018. PMID: 29410444 Free PMC article.

10

The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth.

Liu X, Lu Y, Chen Z, Liu X, Hu W, Zheng L, Chen Y, Kurie JM, Shi M, Mustachio LM, Adresson T, Fox S, Roszik J, Kawakami M, Freemantle SJ, Dmitrovsky E. Liu X, et al. Among authors: chen z, chen y. Mol Cancer Res. 2021 Apr;19(4):667-677. doi: 10.1158/1541-7786.MCR-20-0579. Epub 2020 Dec 30. Mol Cancer Res. 2021. PMID: 33380466 Free PMC article.

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