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Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade.
Goswami S, Raychaudhuri D, Singh P, Natarajan SM, Chen Y, Poon C, Hennessey M, Tannir AJ, Zhang J, Anandhan S, Kerrigan BP, Macaluso MD, He Z, Jindal S, Lang FF, Basu S, Sharma P. Goswami S, et al. Among authors: lang ff. Nat Cancer. 2023 Oct;4(10):1455-1473. doi: 10.1038/s43018-023-00620-0. Epub 2023 Aug 31. Nat Cancer. 2023. PMID: 37653141
Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages.
de Groot J, Penas-Prado M, Alfaro-Munoz K, Hunter K, Pei BL, O'Brien B, Weathers SP, Loghin M, Kamiya Matsouka C, Yung WKA, Mandel J, Wu J, Yuan Y, Zhou S, Fuller GN, Huse J, Rao G, Weinberg JS, Prabhu SS, McCutcheon IE, Lang FF, Ferguson SD, Sawaya R, Colen R, Yadav SS, Blando J, Vence L, Allison J, Sharma P, Heimberger AB. de Groot J, et al. Among authors: lang ff. Neuro Oncol. 2020 Apr 15;22(4):539-549. doi: 10.1093/neuonc/noz185. Neuro Oncol. 2020. PMID: 31755915 Free PMC article.
Current surgical management of glioblastoma.
Hentschel SJ, Lang FF. Hentschel SJ, et al. Among authors: lang ff. Cancer J. 2003 Mar-Apr;9(2):113-25. doi: 10.1097/00130404-200303000-00007. Cancer J. 2003. PMID: 12784877 Review.
ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo.
Alonso MM, Cascallo M, Gomez-Manzano C, Jiang H, Bekele BN, Perez-Gimenez A, Lang FF, Piao Y, Alemany R, Fueyo J. Alonso MM, et al. Among authors: lang ff. Cancer Res. 2007 Sep 1;67(17):8255-63. doi: 10.1158/0008-5472.CAN-06-4675. Cancer Res. 2007. PMID: 17804740
Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway.
Wei J, Barr J, Kong LY, Wang Y, Wu A, Sharma AK, Gumin J, Henry V, Colman H, Priebe W, Sawaya R, Lang FF, Heimberger AB. Wei J, et al. Among authors: lang ff. Mol Cancer Ther. 2010 Jan;9(1):67-78. doi: 10.1158/1535-7163.MCT-09-0734. Epub 2010 Jan 6. Mol Cancer Ther. 2010. PMID: 20053772 Free PMC article.
Glioma-associated cancer-initiating cells induce immunosuppression.
Wei J, Barr J, Kong LY, Wang Y, Wu A, Sharma AK, Gumin J, Henry V, Colman H, Sawaya R, Lang FF, Heimberger AB. Wei J, et al. Among authors: lang ff. Clin Cancer Res. 2010 Jan 15;16(2):461-73. doi: 10.1158/1078-0432.CCR-09-1983. Epub 2010 Jan 12. Clin Cancer Res. 2010. PMID: 20068105 Free PMC article. Retracted.
260 results