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Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression.
J Clin Invest. 2023 Sep 1;133(17):e164258. doi: 10.1172/JCI164258.
J Clin Invest. 2023.
PMID: 37655661
Free PMC article.
Tumor cells fail to present MHC-II-restricted epitopes derived from oncogenes to CD4+ T cells.
Brightman SE, Naradikian MS, Thota RR, Becker A, Montero L, Bahmanof M, Premlal ALR, Greenbaum JA, Peters B, Cohen EE, Miller AM, Schoenberger SP.
Brightman SE, et al. Among authors: thota rr.
JCI Insight. 2023 Jan 24;8(2):e165570. doi: 10.1172/jci.insight.165570.
JCI Insight. 2023.
PMID: 36512410
Free PMC article.
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Linked CD4 + /CD8 + T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression.
Dolina JS, Lee J, Brightman SE, McArdle S, Hall SM, Thota RR, Lanka M, Premlal ALR, Greenbaum JA, Cohen EEW, Peters B, Schoenberger SP.
Dolina JS, et al. Among authors: thota rr.
bioRxiv [Preprint]. 2023 May 7:2023.05.06.539290. doi: 10.1101/2023.05.06.539290.
bioRxiv. 2023.
PMID: 37205330
Free PMC article.
Updated.
Preprint.
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Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors.
Brightman SE, Becker A, Thota RR, Naradikian MS, Chihab L, Zavala KS, Ramamoorthy Premlal AL, Griswold RQ, Dolina JS, Cohen EEW, Miller AM, Peters B, Schoenberger SP.
Brightman SE, et al. Among authors: thota rr.
Nat Immunol. 2023 Aug;24(8):1345-1357. doi: 10.1038/s41590-023-01543-9. Epub 2023 Jul 3.
Nat Immunol. 2023.
PMID: 37400675
Free PMC article.
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Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors.
Brightman SE, Becker A, Thota RR, Naradikian MS, Chihab L, Zavala KS, Ramamoorthy Premlal AL, Griswold RQ, Dolina JS, Cohen EEW, Miller AM, Peters B, Schoenberger SP.
Brightman SE, et al. Among authors: thota rr.
Nat Immunol. 2023 Aug;24(8):1391. doi: 10.1038/s41590-023-01591-1.
Nat Immunol. 2023.
PMID: 37464051
Free PMC article.
No abstract available.
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A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer.
Miller AM, Koşaloğlu-Yalçın Z, Westernberg L, Montero L, Bahmanof M, Frentzen A, Lanka M, Logandha Ramamoorthy Premlal A, Seumois G, Greenbaum J, Brightman SE, Soria Zavala K, Thota RR, Naradikian MS, Makani SS, Lippman SM, Sette A, Cohen EEW, Peters B, Schoenberger SP.
Miller AM, et al. Among authors: thota rr.
Sci Transl Med. 2024 Feb 28;16(736):eabj9905. doi: 10.1126/scitranslmed.abj9905. Epub 2024 Feb 28.
Sci Transl Med. 2024.
PMID: 38416845
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