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Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons.
Truex NL, Mohapatra S, Melo M, Rodriguez J, Li N, Abraham W, Sementa D, Touti F, Keskin DB, Wu CJ, Irvine DJ, Gómez-Bombarelli R, Pentelute BL. Truex NL, et al. Among authors: keskin db. bioRxiv [Preprint]. 2023 Sep 26:2023.08.22.554289. doi: 10.1101/2023.08.22.554289. bioRxiv. 2023. PMID: 37662211 Free PMC article. Updated. Preprint.
Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons.
Truex NL, Mohapatra S, Melo M, Rodriguez J, Li N, Abraham W, Sementa D, Touti F, Keskin DB, Wu CJ, Irvine DJ, Gómez-Bombarelli R, Pentelute BL. Truex NL, et al. Among authors: keskin db. ACS Cent Sci. 2024 Mar 6;10(4):793-802. doi: 10.1021/acscentsci.3c01544. eCollection 2024 Apr 24. ACS Cent Sci. 2024. PMID: 38680558 Free PMC article.
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy.
Bachireddy P, Azizi E, Burdziak C, Nguyen VN, Ennis CS, Maurer K, Park CY, Choo ZN, Li S, Gohil SH, Ruthen NG, Ge Z, Keskin DB, Cieri N, Livak KJ, Kim HT, Neuberg DS, Soiffer RJ, Ritz J, Alyea EP, Pe'er D, Wu CJ. Bachireddy P, et al. Among authors: keskin db. Cell Rep. 2023 Aug 29;42(8):113011. doi: 10.1016/j.celrep.2023.113011. Epub 2023 Aug 8. Cell Rep. 2023. PMID: 37556329 Free PMC article. No abstract available.
Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination.
Zeng YC, Young OJ, Wintersinger CM, Anastassacos FM, MacDonald JI, Isinelli G, Dellacherie MO, Sobral M, Bai H, Graveline AR, Vernet A, Sanchez M, Mulligan K, Choi Y, Ferrante TC, Keskin DB, Fell GG, Neuberg D, Wu CJ, Mooney DJ, Kwon IC, Ryu JH, Shih WM. Zeng YC, et al. Among authors: keskin db. Nat Nanotechnol. 2024 Mar 15. doi: 10.1038/s41565-024-01615-3. Online ahead of print. Nat Nanotechnol. 2024. PMID: 38491184
CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness.
Qin X, Lam A, Zhang X, Sengupta S, Iorgulescu JB, Ni H, Das S, Rager M, Zhou Z, Zuo T, Meara GK, Floru AE, Kemet C, Veerapaneni D, Kashy D, Lin L, Lloyd K, Kwok L, Smith KS, Nagaraju RT, Meijers R, Ceol C, Liu CT, Alexandrescu S, Wu CJ, Keskin DB, George RE, Feng H. Qin X, et al. Among authors: keskin db. Sci Adv. 2024 Mar 15;10(11):eadh9547. doi: 10.1126/sciadv.adh9547. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489372 Free PMC article.
Dictionary of immune responses to cytokines at single-cell resolution.
Cui A, Huang T, Li S, Ma A, Pérez JL, Sander C, Keskin DB, Wu CJ, Fraenkel E, Hacohen N. Cui A, et al. Among authors: keskin db. Nature. 2024 Jan;625(7994):377-384. doi: 10.1038/s41586-023-06816-9. Epub 2023 Dec 6. Nature. 2024. PMID: 38057668 Free PMC article.
Integrated Immunopeptidomic and Proteomic Analysis of COVID-19 lung biopsies.
Yin S, Klaeger S, Chea VA, Carulli IP, Rachimi S, Black KE, Filbin M, Hariri LP, Knipe RS, Padera RF, Stevens JD, Lane WJ, Carr SA, Wu CJ, Kim EY, Keskin DB. Yin S, et al. Among authors: keskin db. Front Immunol. 2023 Oct 20;14:1269335. doi: 10.3389/fimmu.2023.1269335. eCollection 2023. Front Immunol. 2023. PMID: 37942334 Free PMC article.
The BRD4-NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma.
Durall RT, Huang J, Wojenski L, Huang Y, Gokhale PC, Leeper BA, Nash JO, Ballester PL, Davidson S, Shlien A, Sotirakis E, Bertaux F, Dubus V, Luo J, Wu CJ, Keskin DB, Eagen KP, Shapiro GI, French CA. Durall RT, et al. Among authors: keskin db. Cancer Res. 2023 Dec 1;83(23):3846-3860. doi: 10.1158/0008-5472.CAN-23-2545. Cancer Res. 2023. PMID: 37819236 Free PMC article.
97 results