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Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling.
Jiang Y, Gruszka D, Zeng C, Swindell WR, Gaskill C, Sorensen C, Brown W, Gangwar RS, Tsoi LC, Webster J, Sigurðardóttir SL, Sarkar MK, Uppala R, Kidder A, Xing X, Plazyo O, Xing E, Billi AC, Maverakis E, Kahlenberg JM, Gudjonsson JE, Ward NL. Jiang Y, et al. Among authors: ward nl. JCI Insight. 2024 Mar 12;9(8):e172764. doi: 10.1172/jci.insight.172764. JCI Insight. 2024. PMID: 38470486 Free PMC article.
Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis.
Ma F, Plazyo O, Billi AC, Tsoi LC, Xing X, Wasikowski R, Gharaee-Kermani M, Hile G, Jiang Y, Harms PW, Xing E, Kirma J, Xi J, Hsu JE, Sarkar MK, Chung Y, Di Domizio J, Gilliet M, Ward NL, Maverakis E, Klechevsky E, Voorhees JJ, Elder JT, Lee JH, Kahlenberg JM, Pellegrini M, Modlin RL, Gudjonsson JE. Ma F, et al. Among authors: ward nl. Nat Commun. 2023 Jun 12;14(1):3455. doi: 10.1038/s41467-023-39020-4. Nat Commun. 2023. PMID: 37308489 Free PMC article.
Skin codelivery of contact sensitizers and neurokinin-1 receptor antagonists integrated in microneedle arrays suppresses allergic contact dermatitis.
Bandyopadhyay M, Morelli AE, Balmert SC, Ward NL, Erdos G, Sumpter TL, Korkmaz E, Kaplan DH, Oberbarnscheidt MH, Tkacheva O, Shufesky WJ, Falo LD Jr, Larregina AT. Bandyopadhyay M, et al. Among authors: ward nl. J Allergy Clin Immunol. 2022 Jul;150(1):114-130. doi: 10.1016/j.jaci.2021.12.794. Epub 2022 Jan 24. J Allergy Clin Immunol. 2022. PMID: 35085664 Free PMC article.
Mouse Models of Psoriasis: A Comprehensive Review.
Gangwar RS, Gudjonsson JE, Ward NL. Gangwar RS, et al. Among authors: ward nl. J Invest Dermatol. 2022 Mar;142(3 Pt B):884-897. doi: 10.1016/j.jid.2021.06.019. Epub 2021 Dec 23. J Invest Dermatol. 2022. PMID: 34953514 Free PMC article. Review.
Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris.
Shao S, Chen J, Swindell WR, Tsoi LC, Xing X, Ma F, Uppala R, Sarkar MK, Plazyo O, Billi AC, Wasikowski R, Smith KM, Honore P, Scott VE, Maverakis E, Kahlenberg JM, Wang G, Ward NL, Harms PW, Gudjonsson JE. Shao S, et al. Among authors: ward nl. JCI Insight. 2021 Oct 22;6(20):e151911. doi: 10.1172/jci.insight.151911. JCI Insight. 2021. PMID: 34491907 Free PMC article.
IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation.
Gharaee-Kermani M, Estadt SN, Tsoi LC, Wolf-Fortune SJ, Liu J, Xing X, Theros J, Reed TJ, Lowe L, Gruszka D, Ward NL, Gudjonsson JE, Kahlenberg JM. Gharaee-Kermani M, et al. Among authors: ward nl. J Invest Dermatol. 2022 Jan;142(1):155-165.e3. doi: 10.1016/j.jid.2021.05.029. Epub 2021 Aug 5. J Invest Dermatol. 2022. PMID: 34364883 Free PMC article.
123 results