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Complete human day 14 post-implantation embryo models from naive ES cells.
Oldak B, Wildschutz E, Bondarenko V, Comar MY, Zhao C, Aguilera-Castrejon A, Tarazi S, Viukov S, Pham TXA, Ashouokhi S, Lokshtanov D, Roncato F, Ariel E, Rose M, Livnat N, Shani T, Joubran C, Cohen R, Addadi Y, Chemla M, Kedmi M, Keren-Shaul H, Pasque V, Petropoulos S, Lanner F, Novershtern N, Hanna JH. Oldak B, et al. Among authors: hanna jh. Nature. 2023 Oct;622(7983):562-573. doi: 10.1038/s41586-023-06604-5. Epub 2023 Sep 6. Nature. 2023. PMID: 37673118 Free PMC article.
Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis.
Aguilera-Castrejon A, Oldak B, Shani T, Ghanem N, Itzkovich C, Slomovich S, Tarazi S, Bayerl J, Chugaeva V, Ayyash M, Ashouokhi S, Sheban D, Livnat N, Lasman L, Viukov S, Zerbib M, Addadi Y, Rais Y, Cheng S, Stelzer Y, Keren-Shaul H, Shlomo R, Massarwa R, Novershtern N, Maza I, Hanna JH. Aguilera-Castrejon A, et al. Among authors: hanna jh. Nature. 2021 May;593(7857):119-124. doi: 10.1038/s41586-021-03416-3. Epub 2021 Mar 17. Nature. 2021. PMID: 33731940
Universally non-immunogenic iPSCs.
Shani T, Hanna JH. Shani T, et al. Among authors: hanna jh. Nat Biomed Eng. 2019 May;3(5):337-338. doi: 10.1038/s41551-019-0401-8. Nat Biomed Eng. 2019. PMID: 31036889 No abstract available.
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs.
Tarazi S, Aguilera-Castrejon A, Joubran C, Ghanem N, Ashouokhi S, Roncato F, Wildschutz E, Haddad M, Oldak B, Gomez-Cesar E, Livnat N, Viukov S, Lokshtanov D, Naveh-Tassa S, Rose M, Hanna S, Raanan C, Brenner O, Kedmi M, Keren-Shaul H, Lapidot T, Maza I, Novershtern N, Hanna JH. Tarazi S, et al. Among authors: hanna jh. Cell. 2022 Sep 1;185(18):3290-3306.e25. doi: 10.1016/j.cell.2022.07.028. Epub 2022 Aug 1. Cell. 2022. PMID: 35988542 Free PMC article.
The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.
Mansour AA, Gafni O, Weinberger L, Zviran A, Ayyash M, Rais Y, Krupalnik V, Zerbib M, Amann-Zalcenstein D, Maza I, Geula S, Viukov S, Holtzman L, Pribluda A, Canaani E, Horn-Saban S, Amit I, Novershtern N, Hanna JH. Mansour AA, et al. Among authors: hanna jh. Nature. 2012 Aug 16;488(7411):409-13. doi: 10.1038/nature11272. Nature. 2012. PMID: 22801502
Deterministic direct reprogramming of somatic cells to pluripotency.
Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, Mansour AA, Caspi I, Krupalnik V, Zerbib M, Maza I, Mor N, Baran D, Weinberger L, Jaitin DA, Lara-Astiaso D, Blecher-Gonen R, Shipony Z, Mukamel Z, Hagai T, Gilad S, Amann-Zalcenstein D, Tanay A, Amit I, Novershtern N, Hanna JH. Rais Y, et al. Among authors: hanna jh. Nature. 2013 Oct 3;502(7469):65-70. doi: 10.1038/nature12587. Epub 2013 Sep 18. Nature. 2013. PMID: 24048479
97 results