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Serine starvation silences estrogen receptor signaling through histone hypoacetylation.
Li AM, He B, Karagiannis D, Li Y, Jiang H, Srinivasan P, Ramirez Y, Zhou MN, Curtis C, Gruber JJ, Lu C, Rankin EB, Ye J. Li AM, et al. Among authors: karagiannis d. Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2302489120. doi: 10.1073/pnas.2302489120. Epub 2023 Sep 11. Proc Natl Acad Sci U S A. 2023. PMID: 37695911 Free PMC article.
Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma.
Chen X, Li Y, Zhu F, Xu X, Estrella B, Pazos MA 2nd, McGuire JT, Karagiannis D, Sahu V, Mustafokulov M, Scuoppo C, Sánchez-Rivera FJ, Soto-Feliciano YM, Pasqualucci L, Ciccia A, Amengual JE, Lu C. Chen X, et al. Among authors: karagiannis d. Nat Commun. 2023 Jul 17;14(1):4259. doi: 10.1038/s41467-023-39990-5. Nat Commun. 2023. PMID: 37460547 Free PMC article.
Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy.
Zhang Y, Karagiannis D, Liu H, Lin M, Fang Y, Jiang M, Chen X, Suresh S, Huang H, She J, Shi F, Yang P, El-Rifai W, Zaika A, Oro AE, Rustgi AK, Wang TC, Lu C, Que J. Zhang Y, et al. Among authors: karagiannis d. bioRxiv [Preprint]. 2023 Sep 11:2023.09.09.556982. doi: 10.1101/2023.09.09.556982. bioRxiv. 2023. PMID: 37745439 Free PMC article. Preprint.
Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.
Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris PJ, Thomas CJ, Possemato R, Vander Heiden MG, Papagiannakopoulos T. Sayin VI, et al. Among authors: karagiannis d. Elife. 2017 Oct 2;6:e28083. doi: 10.7554/eLife.28083. Elife. 2017. PMID: 28967864 Free PMC article.
A Novel Modified Surgical Approach for FIL SSF Lens.
Batsos G, Bouratzis N, Kontomichos L, Casas DR, Atzamoglou S, Peponis V, Karagiannis D, Paroikakis E. Batsos G, et al. Among authors: karagiannis d. Cureus. 2023 Dec 3;15(12):e49857. doi: 10.7759/cureus.49857. eCollection 2023 Dec. Cureus. 2023. PMID: 38169895 Free PMC article.
Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors.
Nikolaou PE, Lambrinidis G, Georgiou M, Karagiannis D, Efentakis P, Bessis-Lazarou P, Founta K, Kampoukos S, Konstantin V, Palmeira CM, Davidson SM, Lougiakis N, Marakos P, Pouli N, Mikros E, Andreadou I. Nikolaou PE, et al. Among authors: karagiannis d. J Med Chem. 2023 Nov 23;66(22):15115-15140. doi: 10.1021/acs.jmedchem.3c01048. Epub 2023 Nov 9. J Med Chem. 2023. PMID: 37943012
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