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Death-seq identifies regulators of cell death and senolytic therapies.
Colville A, Liu JY, Rodriguez-Mateo C, Thomas S, Ishak HD, Zhou R, Klein JDD, Morgens DW, Goshayeshi A, Salvi JS, Yao D, Spees K, Dixon SJ, Liu C, Rhee JW, Lai C, Wu JC, Bassik MC, Rando TA. Colville A, et al. Among authors: dixon sj. Cell Metab. 2023 Oct 3;35(10):1814-1829.e6. doi: 10.1016/j.cmet.2023.08.008. Epub 2023 Sep 11. Cell Metab. 2023. PMID: 37699398
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA. Bersuker K, et al. Among authors: dixon sj. Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21. Nature. 2019. PMID: 31634900 Free PMC article.
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.
Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA. Li Z, et al. Among authors: dixon sj. Nat Chem Biol. 2022 Jul;18(7):751-761. doi: 10.1038/s41589-022-01033-3. Epub 2022 May 30. Nat Chem Biol. 2022. PMID: 35637349 Free PMC article.
Emerging roles for lipids in non-apoptotic cell death.
Magtanong L, Ko PJ, Dixon SJ. Magtanong L, et al. Among authors: dixon sj. Cell Death Differ. 2016 Jul;23(7):1099-109. doi: 10.1038/cdd.2016.25. Epub 2016 Mar 11. Cell Death Differ. 2016. PMID: 26967968 Free PMC article. Review.
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD. Stockwell BR, et al. Among authors: dixon sj. Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Cell. 2017. PMID: 28985560 Free PMC article. Review.
The impact of non-genetic heterogeneity on cancer cell death.
Inde Z, Dixon SJ. Inde Z, et al. Among authors: dixon sj. Crit Rev Biochem Mol Biol. 2018 Feb;53(1):99-114. doi: 10.1080/10409238.2017.1412395. Epub 2017 Dec 18. Crit Rev Biochem Mol Biol. 2018. PMID: 29250983 Free PMC article. Review.
p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells.
Tarangelo A, Magtanong L, Bieging-Rolett KT, Li Y, Ye J, Attardi LD, Dixon SJ. Tarangelo A, et al. Among authors: dixon sj. Cell Rep. 2018 Jan 16;22(3):569-575. doi: 10.1016/j.celrep.2017.12.077. Cell Rep. 2018. PMID: 29346757 Free PMC article.
262 results