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The clinical utility and costs of whole-genome sequencing to detect cancer susceptibility variants-a multi-site prospective cohort study.
Genome Med. 2023 Sep 19;15(1):74. doi: 10.1186/s13073-023-01223-1.
Genome Med. 2023.
PMID: 37723522
Free PMC article.
A phase 1a/1b first-in-human study (COMPASSION-01) evaluating cadonilimab in patients with advanced solid tumors.
Frentzas S, Gan HK, Cosman R, Coward J, Tran B, Millward M, Zhou Y, Wang W, Xia D, Wang ZM, Li B, Xia M, Desai J.
Frentzas S, et al.
Cell Rep Med. 2023 Nov 21;4(11):101242. doi: 10.1016/j.xcrm.2023.101242. Epub 2023 Oct 17.
Cell Rep Med. 2023.
PMID: 37852261
Free PMC article.
Clinical Trial.
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ATX-101, a cell-penetrating protein targeting PCNA, can be safely administered as intravenous infusion in patients and shows clinical activity in a Phase 1 study.
Lemech CR, Kichenadasse G, Marschner JP, Alevizopoulos K, Otterlei M, Millward M.
Lemech CR, et al.
Oncogene. 2023 Feb;42(7):541-544. doi: 10.1038/s41388-022-02582-6. Epub 2022 Dec 23.
Oncogene. 2023.
PMID: 36564469
Free PMC article.
Clinical Trial.
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Circulating pre-treatment T-cell receptor repertoire as a predictive biomarker in advanced or metastatic non-small-cell lung cancer patients treated with pembrolizumab alone or in combination with chemotherapy.
Abed A, Beasley AB, Reid AL, Law N, Calapre L, Millward M, Lo J, Gray ES.
Abed A, et al.
ESMO Open. 2023 Dec;8(6):102066. doi: 10.1016/j.esmoop.2023.102066. Epub 2023 Nov 22.
ESMO Open. 2023.
PMID: 37995426
Free PMC article.
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