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Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas.
Brekke RS, Gravdal A, El Jellas K, Curry GE, Lin J, Wilhelm SJ, Steine SJ, Mas E, Johansson S, Lowe ME, Johansson BB, Xiao X, Fjeld K, Molven A. Brekke RS, et al. Among authors: steine sj. Hum Mol Genet. 2024 May 18;33(11):1001-1014. doi: 10.1093/hmg/ddae034. Hum Mol Genet. 2024. PMID: 38483348 Free PMC article.
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice.
Fjeld K, Gravdal A, Brekke RS, Alam J, Wilhelm SJ, El Jellas K, Pettersen HN, Lin J, Solheim MH, Steine SJ, Johansson BB, Njølstad PR, Verbeke CS, Xiao X, Lowe ME, Molven A. Fjeld K, et al. Among authors: steine sj. Pancreatology. 2022 Dec;22(8):1099-1111. doi: 10.1016/j.pan.2022.11.003. Epub 2022 Nov 9. Pancreatology. 2022. PMID: 36379850 Free article.
[Palliative treatment of patients with COVID-19].
Brenne AT, Nordbø A, Steine S, Fasting A, Berglund MA, Røynstrand E, Hjorth NE. Brenne AT, et al. Among authors: steine s. Tidsskr Nor Laegeforen. 2020 Apr 3;140(7). doi: 10.4045/tidsskr.20.0276. Print 2020 May 5. Tidsskr Nor Laegeforen. 2020. PMID: 32378853 Free article. Norwegian. No abstract available.
Characterization of CEL-DUP2: Complete duplication of the carboxyl ester lipase gene is unlikely to influence risk of chronic pancreatitis.
Fjeld K, Masson E, Lin JH, Michl P, Stokowy T, Gravdal A, El Jellas K, Steine SJ, Hoem D, Johansson BB, Dalva M, Ruffert C, Zou WB, Li ZS, Njølstad PR, Chen JM, Liao Z, Johansson S, Rosendahl J, Férec C, Molven A. Fjeld K, et al. Among authors: steine sj. Pancreatology. 2020 Apr;20(3):377-384. doi: 10.1016/j.pan.2020.01.011. Epub 2020 Jan 20. Pancreatology. 2020. PMID: 32007358
58 results