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Manipulating mitochondrial electron flow enhances tumor immunogenicity.
Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Mangalhara KC, et al. Among authors: chen d. Science. 2023 Sep 22;381(6664):1316-1323. doi: 10.1126/science.abq1053. Epub 2023 Sep 21. Science. 2023. PMID: 37733872 Free PMC article.
CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.
Chen D, Varanasi SK, Hara T, Traina K, Sun M, McDonald B, Farsakoglu Y, Clanton J, Xu S, Garcia-Rivera L, Mann TH, Du V, Chung HK, Xu Z, Tripple V, Casillas E, Ma S, O'Connor C, Yang Q, Zheng Y, Hunter T, Lemke G, Kaech SM. Chen D, et al. Immunity. 2023 Sep 12;56(9):2086-2104.e8. doi: 10.1016/j.immuni.2023.07.015. Epub 2023 Aug 11. Immunity. 2023. PMID: 37572655
The β1-adrenergic receptor links sympathetic nerves to T cell exhaustion.
Globig AM, Zhao S, Roginsky J, Maltez VI, Guiza J, Avina-Ochoa N, Heeg M, Araujo Hoffmann F, Chaudhary O, Wang J, Senturk G, Chen D, O'Connor C, Pfaff S, Germain RN, Schalper KA, Emu B, Kaech SM. Globig AM, et al. Among authors: chen d. Nature. 2023 Oct;622(7982):383-392. doi: 10.1038/s41586-023-06568-6. Epub 2023 Sep 20. Nature. 2023. PMID: 37731001
Erratum: Author correction to 'FGF4 protects the liver from immune-mediated injury by activating CaMKKβ-PINK1 signal pathway to inhibit hepatocellular apoptosis' [Acta Pharm Sin B 14 (2024) 1605-1623].
Huang Z, Pan T, Xu L, Shi L, Ma X, Zhou L, Wang L, Wang J, Zhu G, Chen D, Song L, Pan X, Wang X, Li X, Luo Y, Chen Y. Huang Z, et al. Among authors: chen d. Acta Pharm Sin B. 2024 Jun;14(6):2791-2793. doi: 10.1016/j.apsb.2024.04.008. Epub 2024 Apr 9. Acta Pharm Sin B. 2024. PMID: 38828151 Free PMC article.
Efficacy of real-time artificial intelligence-aid endoscopic ultrasonography diagnostic system in discriminating gastrointestinal stromal tumors and leiomyomas: a multicenter diagnostic study.
Dong Z, Zhao X, Zheng H, Zheng H, Chen D, Cao J, Xiao Z, Sun Y, Zhuang Q, Wu S, Xia J, Ning M, Qin B, Zhou H, Bao J, Wan X. Dong Z, et al. Among authors: chen d. EClinicalMedicine. 2024 May 24;73:102656. doi: 10.1016/j.eclinm.2024.102656. eCollection 2024 Jul. EClinicalMedicine. 2024. PMID: 38828130 Free PMC article.
Pre-test Prediction of Non-ischemic Cardiomyopathies using Time-Series EHR Data.
Ishwaran K, Abadie BQ, Chen PH, Bolen M, Karamlou T, Grimm R, Tang WHW, Nguyen C, Kwon D, Chen D. Ishwaran K, et al. Among authors: chen d. AMIA Jt Summits Transl Sci Proc. 2024 May 31;2024:239-248. eCollection 2024. AMIA Jt Summits Transl Sci Proc. 2024. PMID: 38827049 Free PMC article.
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