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Page 1
Automated Cytometric Gating with Human-Level Performance Using Bivariate Segmentation.
Chen J, Ionita M, Feng Y, Lu Y, Orzechowski P, Garai S, Hassinger K, Bao J, Wen J, Duong-Tran D, Wagenaar J, McKeague ML, Painter MM, Mathew D, Pattekar A, Meyer NJ, John Wherry E, Greenplate AR, Shen L. Chen J, et al. Among authors: mckeague ml. bioRxiv [Preprint]. 2024 May 9:2024.05.06.592739. doi: 10.1101/2024.05.06.592739. bioRxiv. 2024. PMID: 38766268 Free PMC article. Preprint.
Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection.
Painter MM, Johnston TS, Lundgreen KA, Santos JJS, Qin JS, Goel RR, Apostolidis SA, Mathew D, Fulmer B, Williams JC, McKeague ML, Pattekar A, Goode A, Nasta S, Baxter AE, Giles JR, Skelly AN, Felley LE, McLaughlin M, Weaver J; Penn Medicine BioBank; Kuthuru O, Dougherty J, Adamski S, Long S, Kee M, Clendenin C, da Silva Antunes R, Grifoni A, Weiskopf D, Sette A, Huang AC, Rader DJ, Hensley SE, Bates P, Greenplate AR, Wherry EJ. Painter MM, et al. Among authors: mckeague ml. Nat Immunol. 2023 Oct;24(10):1711-1724. doi: 10.1038/s41590-023-01613-y. Epub 2023 Sep 21. Nat Immunol. 2023. PMID: 37735592
Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection.
McIntosh CM, Allocco JB, Wang P, McKeague ML, Cassano A, Wang Y, Xie SZ, Hynes G, Mora-Cartín R, Abbondanza D, Chen L, Sattar H, Yin D, Zhang ZJ, Chong AS, Alegre ML. McIntosh CM, et al. Among authors: mckeague ml. J Clin Invest. 2023 Nov 1;133(21):e168465. doi: 10.1172/JCI168465. J Clin Invest. 2023. PMID: 37676735 Free PMC article.
Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies.
Painter MM, Johnston TS, Lundgreen KA, Santos JJS, Qin JS, Goel RR, Apostolidis SA, Mathew D, Fulmer B, Williams JC, McKeague ML, Pattekar A, Goode A, Nasta S, Baxter AE, Giles JR, Skelly AN, Felley LE, McLaughlin M, Weaver J; Penn Medicine BioBank; Kuthuru O, Dougherty J, Adamski S, Long S, Kee M, Clendenin C, da Silva Antunes R, Grifoni A, Weiskopf D, Sette A, Huang AC, Rader DJ, Hensley SE, Bates P, Greenplate AR, Wherry EJ. Painter MM, et al. Among authors: mckeague ml. bioRxiv [Preprint]. 2023 Feb 6:2023.02.05.527215. doi: 10.1101/2023.02.05.527215. bioRxiv. 2023. PMID: 36798171 Free PMC article. Updated. Preprint.
Reduced Satb1 expression predisposes CD4+ T conventional cells to Treg suppression and promotes transplant survival.
Gupta PK, Allocco JB, Fraipont JM, McKeague ML, Wang P, Andrade MS, McIntosh C, Chen L, Wang Y, Li Y, Andrade J, Conejo-Garcia JR, Chong AS, Alegre ML. Gupta PK, et al. Among authors: mckeague ml. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2205062119. doi: 10.1073/pnas.2205062119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161903 Free PMC article.