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Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Bravo CP, Giani AM, Perez JM, Zhao Z, Samelson A, Wong MY, Evangelisti A, Fan L, Pozner T, Mercedes M, Ye P, Patel T, Yarahmady A, Carling G, Lee VMY, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L. Bravo CP, et al. Among authors: fan l. bioRxiv [Preprint]. 2023 Jun 22:2023.06.19.544278. doi: 10.1101/2023.06.19.544278. bioRxiv. 2023. PMID: 37745431 Free PMC article. Updated. Preprint.
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MY, Zhu D, Yu F, Xu J, Yarahmady A, Chen H, Huang Y, Amin S, Zacharioudakis E, Chen X, Holtzman DM, Mok SA, Gavathiotis E, Sinha SC, Cheng F, Luo W, Gong S, Gan L. Carling GK, et al. Among authors: fan l. bioRxiv [Preprint]. 2024 Jan 25:2024.01.24.577107. doi: 10.1101/2024.01.24.577107. bioRxiv. 2024. PMID: 38328219 Free PMC article. Preprint.
ScISOr-ATAC reveals convergent and divergent splicing and chromatin specificities between matched cell types across cortical regions, evolution, and in Alzheimer's Disease.
Hu W, Foord C, Hsu J, Fan L, Corley MJ, Bhatia TN, Xu S, Belchikov N, He Y, Pang AP, Lanjewar SN, Jarroux J, Joglekar A, Milner TA, Ndhlovu LC, Zhang J, Butelman E, Sloan SA, Lee VM, Gan L, Tilgner HU. Hu W, et al. Among authors: fan l. bioRxiv [Preprint]. 2024 Feb 28:2024.02.24.581897. doi: 10.1101/2024.02.24.581897. bioRxiv. 2024. PMID: 38464236 Free PMC article. Preprint.
FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease.
Jiang C, Yao D, Liu Z, Zheng Y, Chen M, Yim WY, Zheng Q, Zhang T, Fan L, Fan Z, Geng B, Tian R, Zhou T, Qiao W, Shi J, Li F, Xu L, Huang Y, Dong N. Jiang C, et al. Among authors: fan l. Redox Biol. 2024 May 27;73:103215. doi: 10.1016/j.redox.2024.103215. Online ahead of print. Redox Biol. 2024. PMID: 38810422
9,445 results