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Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection.
Aguilar-Calvo P, Malik A, Sandoval DR, Barback C, Orrù CD, Standke HG, Thomas OR, Dwyer CA, Pizzo DP, Bapat J, Soldau K, Ogawa R, Riley MB, Nilsson KPR, Kraus A, Caughey B, Iliff JJ, Vera DR, Esko JD, Sigurdson CJ. Aguilar-Calvo P, et al. Among authors: nilsson kpr. PLoS Pathog. 2023 Sep 25;19(9):e1011487. doi: 10.1371/journal.ppat.1011487. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747931 Free PMC article.
Prion strain discrimination using luminescent conjugated polymers.
Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Polymenidou M, Schwarz P, Leclerc M, Hammarström P, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. Nat Methods. 2007 Dec;4(12):1023-30. doi: 10.1038/nmeth1131. Epub 2007 Nov 18. Nat Methods. 2007. PMID: 18026110
Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses.
Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, Aguzzi A, Hammarström P, Nilsson KP. Aslund A, et al. ACS Chem Biol. 2009 Aug 21;4(8):673-84. doi: 10.1021/cb900112v. ACS Chem Biol. 2009. PMID: 19624097 Free PMC article.
A molecular switch controls interspecies prion disease transmission in mice.
Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Fernández-Borges N, Schwarz P, Castilla J, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. J Clin Invest. 2010 Jul;120(7):2590-9. doi: 10.1172/JCI42051. Epub 2010 Jun 14. J Clin Invest. 2010. PMID: 20551516 Free PMC article.
Prion strain interactions are highly selective.
Nilsson KP, Joshi-Barr S, Winson O, Sigurdson CJ. Nilsson KP, et al. J Neurosci. 2010 Sep 8;30(36):12094-102. doi: 10.1523/JNEUROSCI.2417-10.2010. J Neurosci. 2010. PMID: 20826672 Free PMC article.
Tracking protein aggregate interactions.
Sigurdson CJ, Bartz JC, Nilsson KP. Sigurdson CJ, et al. Prion. 2011 Apr-Jun;5(2):52-5. doi: 10.4161/pri.5.2.16173. Epub 2011 Apr 1. Prion. 2011. PMID: 21597336 Free PMC article. Review.
150 results