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Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies.
Chong SJF, Zhu F, Dashevsky O, Mizuno R, Lai JX, Hackett L, Ryan CE, Collins MC, Iorgulescu JB, Guièze R, Penailillo J, Carrasco R, Hwang YC, Muñoz DP, Bouhaddou M, Lim YC, Wu CJ, Allan JN, Furman RR, Goh BC, Pervaiz S, Coppé JP, Mitsiades CS, Davids MS. Chong SJF, et al. Among authors: allan jn. J Clin Invest. 2023 Nov 15;133(22):e170169. doi: 10.1172/JCI170169. J Clin Invest. 2023. PMID: 37751299 Free PMC article.
Optimal management of the young patient CLL patient.
Allan JN, Furman RR. Allan JN, et al. Best Pract Res Clin Haematol. 2018 Mar;31(1):73-82. doi: 10.1016/j.beha.2017.10.012. Epub 2017 Nov 20. Best Pract Res Clin Haematol. 2018. PMID: 29452669 Review.
Current trends in the management of Richter's syndrome.
Allan JN, Furman RR. Allan JN, et al. Int J Hematol Oncol. 2019 Jan 8;7(4):IJH09. doi: 10.2217/ijh-2018-0010. eCollection 2018 Dec. Int J Hematol Oncol. 2019. PMID: 30651968 Free PMC article. Review.
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Pastore A, Gaiti F, Lu SX, Brand RM, Kulm S, Chaligne R, Gu H, Huang KY, Stamenova EK, Béguelin W, Jiang Y, Schulman RC, Kim KT, Alonso A, Allan JN, Furman RR, Gnirke A, Wu CJ, Melnick AM, Meissner A, Bernstein BE, Abdel-Wahab O, Landau DA. Pastore A, et al. Among authors: allan jn. Nat Commun. 2019 Apr 23;10(1):1874. doi: 10.1038/s41467-019-09645-5. Nat Commun. 2019. PMID: 31015400 Free PMC article.
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Gaiti F, Chaligne R, Gu H, Brand RM, Kothen-Hill S, Schulman RC, Grigorev K, Risso D, Kim KT, Pastore A, Huang KY, Alonso A, Sheridan C, Omans ND, Biederstedt E, Clement K, Wang L, Felsenfeld JA, Bhavsar EB, Aryee MJ, Allan JN, Furman R, Gnirke A, Wu CJ, Meissner A, Landau DA. Gaiti F, et al. Among authors: allan jn. Nature. 2019 May;569(7757):576-580. doi: 10.1038/s41586-019-1198-z. Epub 2019 May 15. Nature. 2019. PMID: 31092926 Free PMC article.
Bidirectional linkage between the B-cell receptor and NOTCH1 in chronic lymphocytic leukemia and in Richter's syndrome: therapeutic implications.
Arruga F, Bracciamà V, Vitale N, Vaisitti T, Gizzi K, Yeomans A, Coscia M, D'Arena G, Gaidano G, Allan JN, Furman RR, Packham G, Forconi F, Deaglio S. Arruga F, et al. Among authors: allan jn. Leukemia. 2020 Feb;34(2):462-477. doi: 10.1038/s41375-019-0571-0. Epub 2019 Aug 29. Leukemia. 2020. PMID: 31467429 Free article.
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