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α-lipoic acid ameliorates consequences of copper overload by up-regulating selenoproteins and decreasing redox misbalance.
Kabin E, Dong Y, Roy S, Smirnova J, Smith JW, Ralle M, Summers K, Yang H, Dev S, Wang Y, Devenney B, Cole RN, Palumaa P, Lutsenko S. Kabin E, et al. Among authors: cole rn. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2305961120. doi: 10.1073/pnas.2305961120. Epub 2023 Sep 26. Proc Natl Acad Sci U S A. 2023. PMID: 37751556 Free PMC article.
Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain.
Washington-Hughes CL, Roy S, Seneviratne HK, Karuppagounder SS, Morel Y, Jones JW, Zak A, Xiao T, Boronina TN, Cole RN, Bumpus NN, Chang CJ, Dawson TM, Lutsenko S. Washington-Hughes CL, et al. Among authors: cole rn. PLoS Genet. 2023 Jan 10;19(1):e1010558. doi: 10.1371/journal.pgen.1010558. eCollection 2023 Jan. PLoS Genet. 2023. PMID: 36626371 Free PMC article.
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants.
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, Talalay P. Dinkova-Kostova AT, et al. Among authors: cole rn. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11908-13. doi: 10.1073/pnas.172398899. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193649 Free PMC article.
Electrophilic tuning of the chemoprotective natural product sulforaphane.
Ahn YH, Hwang Y, Liu H, Wang XJ, Zhang Y, Stephenson KK, Boronina TN, Cole RN, Dinkova-Kostova AT, Talalay P, Cole PA. Ahn YH, et al. Among authors: cole rn, cole pa. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9590-5. doi: 10.1073/pnas.1004104107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439747 Free PMC article.
178 results