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RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.
Abe Y, Kofman ER, Almeida M, Ouyang Z, Ponte F, Mueller JR, Cruz-Becerra G, Sakai M, Prohaska TA, Spann NJ, Resende-Coelho A, Seidman JS, Stender JD, Taylor H, Fan W, Link VM, Cobo I, Schlachetzki JCM, Hamakubo T, Jepsen K, Sakai J, Downes M, Evans RM, Yeo GW, Kadonaga JT, Manolagas SC, Rosenfeld MG, Glass CK. Abe Y, et al. Among authors: kofman er. Mol Cell. 2023 Oct 5;83(19):3421-3437.e11. doi: 10.1016/j.molcel.2023.08.029. Epub 2023 Sep 25. Mol Cell. 2023. PMID: 37751740 Free article.
Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes.
Brannan KW, Chaim IA, Marina RJ, Yee BA, Kofman ER, Lorenz DA, Jagannatha P, Dong KD, Madrigal AA, Underwood JG, Yeo GW. Brannan KW, et al. Among authors: kofman er. Nat Methods. 2021 May;18(5):507-519. doi: 10.1038/s41592-021-01128-0. Epub 2021 May 7. Nat Methods. 2021. PMID: 33963355 Free PMC article.
Mutational Footprint of Platinum Chemotherapy in a Secondary Thyroid Cancer.
Schiantarelli J, Pappa T, Conway J, Crowdis J, Reardon B, Dietlein F, Huang J, Stanizzi D, Carey E, Bosma-Moody A, Imamovic A, Han S, Camp S, Kofman E, Shannon E, Barletta JA, He MX, Liu D, Park J, Lorch JH, Van Allen EM. Schiantarelli J, et al. JCO Precis Oncol. 2022 Aug;6:e2200183. doi: 10.1200/PO.22.00183. JCO Precis Oncol. 2022. PMID: 36075011 Free PMC article. No abstract available.
Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology.
Reardon B, Moore ND, Moore NS, Kofman E, AlDubayan SH, Cheung ATM, Conway J, Elmarakeby H, Imamovic A, Kamran SC, Keenan T, Keliher D, Konieczkowski DJ, Liu D, Mouw KW, Park J, Vokes NI, Dietlein F, Van Allen EM. Reardon B, et al. Nat Cancer. 2021 Oct;2(10):1102-1112. doi: 10.1038/s43018-021-00243-3. Epub 2021 Sep 30. Nat Cancer. 2021. PMID: 35121878 Free PMC article.
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation.
Abe Y, Kofman ER, Ouyang Z, Cruz-Becerra G, Spann NJ, Seidman JS, Troutman TD, Stender JD, Taylor H, Fan W, Link VM, Shen Z, Sakai J, Downes M, Evans RM, Kadonaga JT, Rosenfeld MG, Glass CK. Abe Y, et al. Among authors: kofman er. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2316104121. doi: 10.1073/pnas.2316104121. Epub 2024 Jan 2. Proc Natl Acad Sci U S A. 2024. PMID: 38165941 Free PMC article.
Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions.
Xiang JS, Mueller JR, Luo EC, Yee BA, Schafer D, Schmok JC, Tan FE, Rothamel K, McVicar RN, Kwong EM, Croker BA, Jones KL, Her HL, Chen CY, Vu AQ, Jin W, Park SS, Le P, Brannan KW, Kofman ER, Li Y, Tankka AT, Dong KD, Song Y, Clark AE, Carlin AF, Van Nostrand EL, Leibel SL, Yeo GW. Xiang JS, et al. Among authors: kofman er. Res Sq [Preprint]. 2022 Mar 17:rs.3.rs-1394331. doi: 10.21203/rs.3.rs-1394331/v1. Res Sq. 2022. PMID: 35313591 Free PMC article. Preprint.
Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions.
Xiang JS, Mueller JR, Luo EC, Yee BA, Schafer D, Schmok JC, Tan FE, Rothamel K, McVicar RN, Kwong EM, Jones KL, Her HL, Chen CY, Vu AQ, Jin W, Park SS, Le P, Brannan KW, Kofman ER, Li Y, Tankka AT, Dong KD, Song Y, Carlin AF, Van Nostrand EL, Leibel SL, Yeo GW. Xiang JS, et al. Among authors: kofman er. bioRxiv [Preprint]. 2022 Feb 23:2022.02.21.481223. doi: 10.1101/2022.02.21.481223. bioRxiv. 2022. PMID: 35233578 Free PMC article. Preprint.